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Catalog Number:
48165
CAS Number:
142810-19-3
Fmoc-Val-Gly-OH
Purity:
≥ 98% (HPLC)
Synonym(s):
Na-Fmoc-L-valylglycine
Documents
$40.00 /250MG
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Product Information

Fmoc-Val-Gly-OH is a highly versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative, known for its protective Fmoc (fluorenylmethyloxycarbonyl) group, facilitates the efficient assembly of peptides by providing a stable and easily removable protecting group. Its unique structure allows for the incorporation of valine and glycine residues, making it an essential building block in the creation of complex peptides and proteins. Researchers and industry professionals appreciate its role in enhancing the purity and yield of synthesized peptides, which is critical in pharmaceutical applications.

In addition to its importance in peptide synthesis, Fmoc-Val-Gly-OH is also employed in various research applications, including the development of therapeutic agents and biomaterials. Its compatibility with automated synthesizers streamlines the synthesis process, making it a preferred choice for laboratories focused on high-throughput peptide production. The compound's stability and ease of use provide significant advantages over similar compounds, ensuring reliable results in both academic and industrial settings.

Synonyms
Na-Fmoc-L-valylglycine
CAS Number
142810-19-3
Purity
≥ 98% (HPLC)
Molecular Formula
C22H24N2O5
Molecular Weight
396.44
MDL Number
MFCD18427309
Melting Point
198 - 204 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -13.7 ± 5 ° (C=1 in DMF)
Conditions
Store at RT
General Information
Synonyms
Na-Fmoc-L-valylglycine
CAS Number
142810-19-3
Purity
≥ 98% (HPLC)
Molecular Formula
C22H24N2O5
Molecular Weight
396.44
MDL Number
MFCD18427309
Melting Point
198 - 204 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -13.7 ± 5 ° (C=1 in DMF)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Val-Gly-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides. Its protective Fmoc group allows for selective deprotection, facilitating the stepwise assembly of complex peptide chains.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs, which can target specific biological pathways. This specificity can lead to more effective treatments with fewer side effects.
  • Bioconjugation: The compound is employed in bioconjugation processes, where it helps attach peptides to other molecules, such as antibodies or drugs, enhancing their delivery and efficacy in therapeutic applications.
  • Research in Protein Engineering: It plays a role in the design of novel proteins and enzymes, allowing researchers to explore new functionalities and improve existing biological systems.
  • Diagnostics: Fmoc-Val-Gly-OH is used in the development of diagnostic tools, particularly in assays that require specific peptide interactions, aiding in disease detection and monitoring.

Citations