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Catalog Number:
48164
Fmoc-Tyr(tBu)-Aib-OH
Purity:
≥ 95%
Synonym(s):
Fmoc-O-(tert-butyl)-L-tyrosinyl-á-aminoisobutyric acid
Documents
$30.00 /100MG
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Product Information

Fmoc-Tyr(tBu)-Aib-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethyloxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of the amino group during solid-phase peptide synthesis. The presence of the t-butyl (tBu) side chain enhances the compound's hydrophobicity, making it particularly useful in the synthesis of peptides that require specific folding or stability. Additionally, the incorporation of Aib (α-aminoisobutyric acid) contributes to the formation of helical structures, which are crucial in the design of biologically active peptides.

Researchers and industry professionals can leverage Fmoc-Tyr(tBu)-Aib-OH in various applications, including the development of peptide-based therapeutics, vaccine candidates, and biomaterials. Its unique properties allow for the fine-tuning of peptide sequences to achieve desired biological activities, making it an invaluable tool in medicinal chemistry and biochemistry. Whether you are working on drug discovery or exploring new peptide formulations, this compound offers the reliability and performance needed for successful outcomes.

Synonyms
Fmoc-O-(tert-butyl)-L-tyrosinyl-á-aminoisobutyric acid
Purity
≥ 95%
Molecular Formula
C32H36N2O6
Molecular Weight
544.6
Appearance
White solid
Optical Rotation
[a]D20 = -13.3 ± 5 ° (C=1 MeOH)
Conditions
Store at RT
General Information
Synonyms
Fmoc-O-(tert-butyl)-L-tyrosinyl-á-aminoisobutyric acid
Purity
≥ 95%
Molecular Formula
C32H36N2O6
Molecular Weight
544.6
Appearance
White solid
Optical Rotation
[a]D20 = -13.3 ± 5 ° (C=1 MeOH)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Tyr(tBu)-Aib-OH is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences.
  • Drug Development: It is used in the development of peptide-based drugs, where its unique properties can enhance the efficacy and stability of therapeutic peptides.
  • Bioconjugation: The compound can be employed in bioconjugation techniques, aiding in the attachment of peptides to various biomolecules for targeted drug delivery systems.
  • Research in Neuroscience: Fmoc-Tyr(tBu)-Aib-OH is utilized in studies related to neuropeptides, contributing to the understanding of neurotransmitter functions and interactions.
  • Protein Engineering: It plays a role in protein engineering, where modifications can be made to enhance protein stability and functionality, particularly in therapeutic applications.

Citations