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Catalog Number:
48163
CAS Number:
251316-94-6
Fmoc-Trp-Pro-OH
Purity:
≥ 98% (HPLC)
Synonym(s):
Na-Fmoc-L-tryptophyl-L-proline
Documents
$30.00 /100MG
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Product Information

Fmoc-Trp-Pro-OH is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This amino acid derivative, characterized by its fluorenylmethoxycarbonyl (Fmoc) protecting group, is particularly valuable in solid-phase peptide synthesis (SPPS), where it facilitates the selective protection of amino groups. Its unique structure not only enhances the stability of the peptide chain during synthesis but also allows for easy cleavage under mild conditions, making it an ideal choice for researchers aiming to develop complex peptides with high purity and yield.

In addition to its role in peptide synthesis, Fmoc-Trp-Pro-OH is also significant in the study of protein interactions and drug design. Its indole side chain contributes to the compound's ability to mimic natural peptides, providing insights into biological processes and potential therapeutic applications. Researchers in the fields of biochemistry and pharmacology will find this compound essential for advancing their work in peptide-based drug discovery and development.

Synonyms
Na-Fmoc-L-tryptophyl-L-proline
CAS Number
251316-94-6
Purity
≥ 98% (HPLC)
Molecular Formula
C31H29N3O5
Molecular Weight
523.58
MDL Number
MFCD00672335
Appearance
White to off-white powder
Conditions
Store at RT
General Information
Synonyms
Na-Fmoc-L-tryptophyl-L-proline
CAS Number
251316-94-6
Purity
≥ 98% (HPLC)
Molecular Formula
C31H29N3O5
Molecular Weight
523.58
MDL Number
MFCD00672335
Appearance
White to off-white powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Trp-Pro-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis. Its protective Fmoc group allows for selective deprotection, facilitating the assembly of complex peptide sequences.
  • Drug Development: In pharmaceutical research, it serves as a precursor for designing peptide-based drugs, especially those targeting specific receptors. Its structural properties enhance the stability and efficacy of therapeutic peptides.
  • Bioconjugation: Researchers use this compound to create bioconjugates for targeted drug delivery systems. Its ability to form stable linkages with various biomolecules aids in developing innovative therapies.
  • Protein Engineering: In the field of biotechnology, it is employed in modifying proteins to improve their functionality. This is particularly useful in enzyme engineering and antibody development.
  • Research in Neuroscience: The compound is also explored in studies related to neuropeptides, contributing to the understanding of neurobiological processes and potential treatments for neurological disorders.

Citations