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Catalog Number:
48162
CAS Number:
1456878-79-7
Fmoc-Thr(tBu)-Gly-OH
Purity:
≥ 95%
Synonym(s):
Fmoc-O-(tert-butyl)-L-threoninylglycine
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Product Information

Fmoc-Thr(tBu)-Gly-OH is a valuable compound in the field of peptide synthesis and drug development. This protected amino acid derivative features a fluorenylmethyloxycarbonyl (Fmoc) group, which is widely used in solid-phase peptide synthesis (SPPS) due to its stability and ease of removal under mild conditions. The presence of the threonine (Thr) and glycine (Gly) residues enhances its utility in creating peptides with specific biological activities, making it an essential building block for researchers in medicinal chemistry and biochemistry.

This compound is particularly advantageous for synthesizing peptides that require precise control over stereochemistry and functional group placement. Its unique structure allows for the introduction of various side chains, facilitating the development of peptides with tailored properties for therapeutic applications. Fmoc-Thr(tBu)-Gly-OH is ideal for researchers aiming to explore peptide-based drugs, biomaterials, and other innovative applications in pharmaceutical research.

Synonyms
Fmoc-O-(tert-butyl)-L-threoninylglycine
CAS Number
1456878-79-7
Purity
≥ 95%
Molecular Formula
C25H30N2O6
Molecular Weight
454.52
MDL Number
MFCD18427308
Appearance
White to off-white powder
Conditions
Store at ≤ -10 °C
General Information
Synonyms
Fmoc-O-(tert-butyl)-L-threoninylglycine
CAS Number
1456878-79-7
Purity
≥ 95%
Molecular Formula
C25H30N2O6
Molecular Weight
454.52
MDL Number
MFCD18427308
Appearance
White to off-white powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Thr(tBu)-Gly-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a building block in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently.
  • Drug Development: It is used in the design of peptide-based drugs, particularly in targeting specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The compound facilitates the attachment of peptides to various biomolecules, aiding in the development of targeted drug delivery systems.
  • Analytical Chemistry: It is employed in the preparation of standards for chromatographic techniques, helping to ensure accurate quantification of peptides in biological samples.
  • Research in Proteomics: This compound plays a role in studying protein interactions and functions, contributing to advancements in understanding cellular mechanisms.

Citations