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Catalog Number:
48161
CAS Number:
81672-17-5
Fmoc-Ser(tBu)-Gly-OH
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-O-(tert-butyl)-L-serylglycine
Documents
$50.00 /250MG
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Product Information

Fmoc-Ser(tBu)-Gly-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amine functionalities during the synthesis of peptides. Its t-butyl (tBu) side chain enhances the stability and solubility of the compound, making it particularly advantageous in solid-phase peptide synthesis (SPPS). Researchers and industry professionals appreciate its role in facilitating the formation of complex peptides, which are crucial in pharmaceuticals, particularly in the development of therapeutic proteins and vaccines.

With its unique structure, Fmoc-Ser(tBu)-Gly-OH allows for efficient coupling reactions, ensuring high yields and purity in peptide synthesis. This compound is especially relevant in the fields of biochemistry and medicinal chemistry, where precise control over peptide sequences is vital. Its application extends to the creation of peptide-based drugs, where the incorporation of serine and glycine residues can enhance biological activity and specificity. By choosing Fmoc-Ser(tBu)-Gly-OH, researchers can streamline their synthesis processes while achieving the desired outcomes in their projects.

Synonyms
Fmoc-O-(tert-butyl)-L-serylglycine
CAS Number
81672-17-5
Purity
≥ 98% (HPLC)
Molecular Formula
C24H28N2O6
Molecular Weight
440.5
MDL Number
MFCD18427306
Appearance
White to off-white powder
Conditions
Store at RT
General Information
Synonyms
Fmoc-O-(tert-butyl)-L-serylglycine
CAS Number
81672-17-5
Purity
≥ 98% (HPLC)
Molecular Formula
C24H28N2O6
Molecular Weight
440.5
MDL Number
MFCD18427306
Appearance
White to off-white powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Ser(tBu)-Gly-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity and yield.
  • Bioconjugation: It is used in bioconjugation techniques to attach peptides to other biomolecules, enhancing the development of targeted drug delivery systems and improving the efficacy of therapeutic agents.
  • Drug Development: Researchers leverage this compound in the design of novel drugs, particularly in the field of oncology, where peptide-based therapeutics are gaining traction for their specificity and reduced side effects.
  • Protein Engineering: This chemical plays a significant role in protein engineering, enabling scientists to modify proteins for improved stability and functionality, which is crucial in biopharmaceutical applications.
  • Diagnostics: It is also utilized in the development of diagnostic tools, where peptides derived from this compound can be used as biomarkers for disease detection, enhancing the accuracy of medical tests.

Citations