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Catalog Number:
48157
CAS Number:
239798-78-8
Fmoc-Lys(Boc)-Gly-OH
Purity:
≥ 98% (HPLC)
Synonym(s):
Na-Fmoc-Ne-Boc-L-lysinylglycine
Documents
$55.00 /250MG
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Product Information

Fmoc-Lys(Boc)-Gly-OH is a versatile amino acid derivative widely utilized in peptide synthesis and bioconjugation applications. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during solid-phase peptide synthesis. The Boc (tert-butyloxycarbonyl) group further enhances its stability and compatibility in various chemical reactions. Researchers and industry professionals appreciate its role in facilitating the synthesis of complex peptides and proteins, making it an invaluable tool in drug development and biomolecular research.

With its unique structure, Fmoc-Lys(Boc)-Gly-OH allows for the introduction of lysine and glycine residues into peptides, which can significantly enhance the biological activity and stability of therapeutic agents. Its applications extend to the development of targeted drug delivery systems and the creation of peptide-based vaccines. The compound's ability to undergo selective deprotection under mild conditions makes it particularly advantageous compared to other protecting groups, ensuring high yields and purity in peptide synthesis.

Synonyms
Na-Fmoc-Ne-Boc-L-lysinylglycine
CAS Number
239798-78-8
Purity
≥ 98% (HPLC)
Molecular Formula
C28H35N3O7
Molecular Weight
525.59
MDL Number
MFCD31380727
Density
1.233
Appearance
White powder
Conditions
Store at RT
General Information
Synonyms
Na-Fmoc-Ne-Boc-L-lysinylglycine
CAS Number
239798-78-8
Purity
≥ 98% (HPLC)
Molecular Formula
C28H35N3O7
Molecular Weight
525.59
MDL Number
MFCD31380727
Density
1.233
Appearance
White powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Lys(Boc)-Gly-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis. Its protective groups allow for selective reactions, making it easier to construct complex peptide chains.
  • Drug Development: In pharmaceutical research, it plays a role in developing peptide-based drugs. Its structure can enhance the stability and bioavailability of therapeutic peptides, improving their effectiveness.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps link peptides to other biomolecules, such as antibodies or enzymes, facilitating targeted drug delivery systems.
  • Protein Engineering: Researchers utilize it in protein engineering to modify proteins for specific functions, enhancing their properties for industrial applications, such as in enzyme production.
  • Diagnostics: It finds applications in diagnostic assays, where modified peptides can serve as biomarkers or detection agents, improving the sensitivity and specificity of tests.

Citations