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Catalog Number:
48153
CAS Number:
660846-80-0
Fmoc-Arg(Pbf)-Gly-OH
Purity:
≥ 99% (Chiral HPLC)
Synonym(s):
Na-Fmoc-Nw-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-argininylglycine
Documents
$30.00 /100MG
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Product Information

Fmoc-Arg(Pbf)-Gly-OH is a highly specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound, characterized by its unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, is particularly valued in solid-phase peptide synthesis (SPPS) due to its ability to enhance the stability and solubility of peptides during the synthesis process. Its structure includes an arginine residue protected by a Pbf (2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl) group, making it an ideal choice for researchers focusing on the development of complex peptides and proteins.

In practical applications, Fmoc-Arg(Pbf)-Gly-OH is utilized in the synthesis of bioactive peptides, which can be critical in pharmaceutical research, particularly in the development of therapeutics targeting various diseases. Its unique properties allow for selective reactions and modifications, enabling the creation of peptides with enhanced biological activity. This compound is essential for researchers looking to streamline their peptide synthesis processes while ensuring high purity and yield, making it a valuable addition to any laboratory focused on peptide chemistry.

Synonyms
Na-Fmoc-Nw-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-argininylglycine
CAS Number
660846-80-0
Purity
≥ 99% (Chiral HPLC)
Molecular Formula
C36H43N5O8S
Molecular Weight
705.82
MDL Number
MFCD30475792
Appearance
Off-white solid
Conditions
Store at RT
General Information
Synonyms
Na-Fmoc-Nw-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-argininylglycine
CAS Number
660846-80-0
Purity
≥ 99% (Chiral HPLC)
Molecular Formula
C36H43N5O8S
Molecular Weight
705.82
MDL Number
MFCD30475792
Appearance
Off-white solid
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Arg(Pbf)-Gly-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for various applications in drug development and biotechnology.
  • Drug Development: Its role in the design of peptide-based therapeutics makes it valuable in pharmaceutical research, particularly for developing targeted therapies in cancer and autoimmune diseases.
  • Bioconjugation: The compound can be used in bioconjugation processes, facilitating the attachment of peptides to other molecules, such as antibodies or nanoparticles, enhancing drug delivery systems.
  • Research in Neuroscience: It is employed in studies related to neuropeptides, helping scientists understand signaling pathways and potential treatments for neurological disorders.
  • Protein Engineering: The versatility of this compound allows for modifications in protein structures, aiding in the design of proteins with improved stability and functionality for industrial applications.

Citations