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Catalog Number:
48039
CAS Number:
957-77-7
5-Hydroxyuridine
Purity:
≥ 95% (HPLC)
Synonym(s):
5-Hydroxy-U, 1-β-D-Ribofuranosylisobarbituric acid
Documents
$551.10 /100MG
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Product Information

5-Hydroxyuridine is a versatile nucleoside analog that plays a significant role in various biochemical applications. This compound is recognized for its potential in enhancing RNA synthesis and has been studied for its implications in antiviral therapies and cellular metabolism. Its unique structure allows it to act as a substrate for RNA polymerases, making it a valuable tool in molecular biology research. Researchers have utilized 5-Hydroxyuridine in studies focused on the modulation of gene expression and the development of therapeutic agents against viral infections, particularly in the context of RNA viruses.

Additionally, 5-Hydroxyuridine exhibits antioxidant properties, which may contribute to cellular protection mechanisms. Its ability to stabilize RNA structures can be particularly beneficial in the formulation of RNA-based therapeutics and vaccines. The compound's relevance extends to the fields of pharmacology and biotechnology, where it is employed in the design of innovative treatments and research methodologies. With its multifaceted applications, 5-Hydroxyuridine stands out as a crucial compound for professionals seeking to advance their work in molecular biology and therapeutic development.

Synonyms
5-Hydroxy-U, 1-β-D-Ribofuranosylisobarbituric acid
CAS Number
957-77-7
Purity
≥ 95% (HPLC)
Molecular Formula
C9H12N2O7
Molecular Weight
260.2
MDL Number
MFCD00010571
Melting Point
244 - 246 °C
Appearance
White to light yellow powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
5-Hydroxy-U, 1-β-D-Ribofuranosylisobarbituric acid
CAS Number
957-77-7
Purity
≥ 95% (HPLC)
Molecular Formula
C9H12N2O7
Molecular Weight
260.2
MDL Number
MFCD00010571
Melting Point
244 - 246 °C
Appearance
White to light yellow powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Hydroxyuridine is widely utilized in research focused on:

  • Pharmaceutical Development: This compound plays a crucial role in the synthesis of antiviral drugs, particularly those targeting RNA viruses. Its structural similarity to nucleosides allows it to interfere with viral replication.
  • Biochemical Research: Researchers use 5-Hydroxyuridine to study RNA metabolism and modification processes. Its incorporation into RNA can help elucidate the roles of various modifications in gene expression.
  • Cell Culture Applications: In cell culture systems, it serves as a supplement to enhance cell viability and proliferation, especially in studies involving neuronal cells, where it can support growth and differentiation.
  • Diagnostics: This compound is explored as a potential biomarker in certain diseases. Its levels can be indicative of cellular stress or viral infections, aiding in the development of diagnostic assays.
  • Gene Therapy: 5-Hydroxyuridine is being investigated for its potential in gene therapy applications, where it may enhance the delivery and expression of therapeutic genes by modifying RNA stability.

Citations