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Catalog Number:
48036
CAS Number:
10212-16-5
2'-Fluoro-4-thio-2'-deoxyuridine
Purity:
≥ 95% (HPLC)
Synonym(s):
2'-F-4-thio-2'-dC, 1-(2-Deoxy-2-fluoro-b-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
Documents
$61.60 /25MG
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Product Information

2'-Deoxy-2'-fluoro-4-thiouridine is a modified nucleoside that plays a significant role in molecular biology and pharmaceutical research. This compound is particularly valuable in the development of antiviral and anticancer therapies due to its ability to mimic natural nucleosides while providing enhanced stability and efficacy. Its unique structure allows it to interfere with nucleic acid synthesis, making it a potent candidate for use in drug formulations targeting viral infections and certain types of cancer. Researchers have utilized 2'-Deoxy-2'-fluoro-4-thiouridine in various studies to explore its potential as a therapeutic agent, showcasing its relevance in the ongoing search for effective treatments.

In addition to its applications in drug development, this compound is also instrumental in biochemical assays and research focused on nucleic acid interactions. Its ability to modify RNA and DNA structures opens avenues for innovative research methodologies, particularly in the fields of genetics and molecular diagnostics. The compound's stability and compatibility with existing nucleic acid technologies make it an attractive option for researchers looking to enhance their experimental outcomes. With its promising applications and unique properties, 2'-Deoxy-2'-fluoro-4-thiouridine stands out as a crucial tool in advancing scientific knowledge and therapeutic strategies.

Synonyms
2'-F-4-thio-2'-dC, 1-(2-Deoxy-2-fluoro-b-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
CAS Number
10212-16-5
Purity
≥ 95% (HPLC)
Molecular Formula
C9H11FN2O4S
Molecular Weight
262.26
MDL Number
MFCD30570247
Appearance
White to yellow powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2'-F-4-thio-2'-dC, 1-(2-Deoxy-2-fluoro-b-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
CAS Number
10212-16-5
Purity
≥ 95% (HPLC)
Molecular Formula
C9H11FN2O4S
Molecular Weight
262.26
MDL Number
MFCD30570247
Appearance
White to yellow powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2'-Deoxy-2'-fluoro-4-thiouridine is widely utilized in research focused on:

  • Antiviral Drug Development: This compound serves as a crucial building block in the synthesis of antiviral agents, particularly for targeting RNA viruses. Its unique structure enhances efficacy against viral replication.
  • Gene Therapy: It is employed in the design of modified nucleotides for gene therapy applications, improving the stability and effectiveness of therapeutic oligonucleotides.
  • Research in Cancer Treatment: The compound is being investigated for its potential to inhibit tumor growth by interfering with nucleic acid synthesis, making it a candidate for novel cancer therapies.
  • Diagnostics: It is used in the development of diagnostic tools, particularly in the detection of viral infections through advanced molecular techniques, enhancing accuracy and speed.
  • Biochemical Research: This compound aids researchers in studying nucleic acid interactions and modifications, providing insights into cellular processes and disease mechanisms.

Citations