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Catalog Number:
48032
CAS Number:
2140-67-2
N,N-Dimethylguanosine
Purity:
≥ 95% (HPLC)
Synonym(s):
2-(Dimethylamino)guanosine, 2-Dimethylamino-6-oxypurine riboside
Documents
$211.20 /25MG
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Product Information

N,N-Dimethylguanosine is a modified nucleoside that plays a crucial role in various biological processes, particularly in RNA metabolism. This compound is recognized for its unique ability to enhance the stability and functionality of RNA molecules, making it a valuable tool in molecular biology and biochemistry. Researchers utilize N,N-Dimethylguanosine in the synthesis of RNA oligonucleotides, where it serves as a protective modification that can improve the resistance of RNA to enzymatic degradation. Its application extends to the development of RNA-based therapeutics and diagnostics, where stability and efficacy are paramount.

In addition to its role in RNA research, N,N-Dimethylguanosine is also explored in the field of epigenetics, where it may influence gene expression through its interactions with RNA-binding proteins. This compound's unique properties make it an essential component for scientists looking to innovate in RNA technology and therapeutic development. With its increasing relevance in cutting-edge research, N,N-Dimethylguanosine stands out as a compound of interest for both academic and industrial applications.

Synonyms
2-(Dimethylamino)guanosine, 2-Dimethylamino-6-oxypurine riboside
CAS Number
2140-67-2
Purity
≥ 95% (HPLC)
Molecular Formula
C12H17N5O5
Molecular Weight
311.3
MDL Number
MFCD00057049
Melting Point
239 °C(dec.)
Appearance
White to light yellow to light orange pow
Optical Rotation
[a]D20 = -37 to -33 ° (C=0.1 in 1M NaOH sol.)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-(Dimethylamino)guanosine, 2-Dimethylamino-6-oxypurine riboside
CAS Number
2140-67-2
Purity
≥ 95% (HPLC)
Molecular Formula
C12H17N5O5
Molecular Weight
311.3
MDL Number
MFCD00057049
Melting Point
239 °C(dec.)
Appearance
White to light yellow to light orange pow
Optical Rotation
[a]D20 = -37 to -33 ° (C=0.1 in 1M NaOH sol.)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N,N-Dimethylguanosine is widely utilized in research focused on:

  • Nucleic Acid Research: It serves as a building block in the synthesis of RNA molecules, aiding in the study of RNA structure and function.
  • Biochemical Assays: This compound is used in various assays to investigate enzyme activity, particularly in studies involving RNA methylation.
  • Pharmaceutical Development: It plays a role in drug formulation, especially in the development of antiviral and anticancer therapies that target RNA processes.
  • Diagnostics: N,N-Dimethylguanosine is utilized in the development of diagnostic tools for detecting RNA modifications, which can indicate disease states.
  • Gene Expression Studies: Researchers use it to analyze gene expression patterns, providing insights into cellular responses and regulatory mechanisms.

Citations