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Catalog Number:
47726
CAS Number:
2375587-79-2
Fmoc-4-Azidomethyl-L-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-Phe(4-CH2-N3)-OH
Antibiotic
Documents
$105.00 /25MG
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Product Information

Fmoc-4-Azidomethyl-L-phenylalanine is a versatile building block in peptide synthesis, particularly valued for its unique azide functional group, which allows for selective reactions in bioconjugation and click chemistry applications. This compound is particularly useful for researchers in the fields of medicinal chemistry and biochemistry, as it facilitates the incorporation of bioactive moieties into peptides, enhancing their therapeutic potential. Its Fmoc protecting group ensures compatibility with standard solid-phase peptide synthesis techniques, making it an ideal choice for the development of complex peptide structures.

In addition to its role in peptide synthesis, Fmoc-4-Azidomethyl-L-phenylalanine can be employed in the creation of novel drug delivery systems and targeted therapies. The azide group can participate in various coupling reactions, allowing for the attachment of fluorescent tags or other functional groups, which can be crucial for tracking and studying biological processes. This compound stands out for its ability to streamline the synthesis of multifunctional peptides, providing researchers with a powerful tool to explore new therapeutic avenues.

Synonyms
Fmoc-Phe(4-CH2-N3)-OH
CAS Number
2375587-79-2
Purity
≥ 98% (HPLC)
Molecular Formula
C25H22N4O4
Molecular Weight
442.5
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -30 to -26 ° (C=1 in DMF)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Fmoc-Phe(4-CH2-N3)-OH
CAS Number
2375587-79-2
Purity
≥ 98% (HPLC)
Molecular Formula
C25H22N4O4
Molecular Weight
442.5
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -30 to -26 ° (C=1 in DMF)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-Azidomethyl-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for various biological studies.
  • Click Chemistry: Its azide group enables efficient click chemistry reactions, facilitating the development of bioconjugates and drug delivery systems in pharmaceutical research.
  • Protein Labeling: The compound can be used for labeling proteins with fluorescent tags, aiding in the visualization and tracking of proteins in cellular studies.
  • Drug Development: Its unique properties make it valuable in the design of novel therapeutics, particularly in targeting specific biological pathways.
  • Biomaterials: Fmoc-4-Azidomethyl-L-phenylalanine can be incorporated into biomaterials for tissue engineering, enhancing the functionality and biocompatibility of scaffolds.

Citations