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Catalog Number:
47721
CAS Number:
335164-29-9
N-Fmoc-(4S-NH-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-proline
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-Pro(4S-NH-ivDde)-OH
Documents
$70.00 /25MG
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Product Information

N-Fmoc-(4S-NH-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-proline) is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued for its ability to serve as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups. Its unique structure, featuring a fluorenylmethoxycarbonyl (Fmoc) group, enhances stability and solubility, making it an excellent choice for researchers focused on developing complex peptides and biologically active compounds.

In the pharmaceutical and biotechnology industries, N-Fmoc-(4S-NH-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-proline) is utilized in the design of peptide-based therapeutics, particularly in the creation of cyclic peptides that exhibit improved bioactivity and stability. Its ability to facilitate the synthesis of diverse peptide sequences opens up new avenues for drug discovery and development. Researchers appreciate its compatibility with various coupling reagents and its effectiveness in generating high-purity products, making it a valuable asset in both academic and industrial laboratories.

Synonyms
Fmoc-Pro(4S-NH-ivDde)-OH
CAS Number
335164-29-9
Purity
≥ 98% (HPLC)
Molecular Formula
C33H38N2O6
Molecular Weight
558.7
Appearance
White crystalline powder
Optical Rotation
[α]D20 = +22.0 to +26.0° (C = 1 in MeOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Fmoc-Pro(4S-NH-ivDde)-OH
CAS Number
335164-29-9
Purity
≥ 98% (HPLC)
Molecular Formula
C33H38N2O6
Molecular Weight
558.7
Appearance
White crystalline powder
Optical Rotation
[α]D20 = +22.0 to +26.0° (C = 1 in MeOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-Fmoc-(4S-NH-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without affecting the overall structure. This is crucial for creating complex peptides with specific functions.
  • Drug Development: It plays a significant role in the pharmaceutical industry, particularly in designing peptide-based drugs. Its unique structure can enhance the bioavailability and stability of therapeutic peptides, making it valuable in drug formulation.
  • Bioconjugation: The compound is used in bioconjugation techniques to link peptides to other biomolecules, such as antibodies or enzymes. This application is essential in developing targeted therapies and diagnostic tools in biotechnology.
  • Research in Neuroscience: It is utilized in studies related to neuropeptides, which are crucial for understanding various neurological functions and disorders. The ability to modify neuropeptides can lead to new insights into brain chemistry.
  • Material Science: The compound can be incorporated into polymer systems to create smart materials with responsive properties. This application is beneficial in developing advanced materials for sensors and drug delivery systems.

Citations