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Catalog Number:
47692
CAS Number:
2124196-74-1
Fmoc-a-Me-L-Arg(Pbf)-OH
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
(S)-N-a-Fmoc-C-a-N'-Pbf-arginine
Documents
$110.00 /25MG
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Product Information

Fmoc-a-Me-L-Arg(Pbf)-OH is a highly specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely recognized for its effectiveness in solid-phase peptide synthesis, allowing for the selective protection of amino groups during the synthesis process. The presence of the Pbf (2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl) sulfonyl group enhances the compound's stability and solubility, making it an excellent choice for researchers focused on developing complex peptides and proteins.

This compound is particularly valuable in the fields of medicinal chemistry and biochemistry, where it is utilized to create peptide-based therapeutics and research tools. Its unique structure allows for the incorporation of arginine into peptides, which can enhance biological activity and improve pharmacokinetic properties. Researchers can leverage Fmoc-a-Me-L-Arg(Pbf)-OH to explore novel therapeutic avenues, including targeted drug delivery systems and the development of peptide hormones. With its robust performance in peptide synthesis, this compound stands out as a vital resource for professionals aiming to innovate in peptide chemistry.

Synonyms
(S)-N-a-Fmoc-C-a-N'-Pbf-arginine
CAS Number
2124196-74-1
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C35H42N4O7S
Molecular Weight
662.8
Appearance
Off-white solid
Optical Rotation
[a]D20 = 9 ± 1 ° (C=1 in CHCl3)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(S)-N-a-Fmoc-C-a-N'-Pbf-arginine
CAS Number
2124196-74-1
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C35H42N4O7S
Molecular Weight
662.8
Appearance
Off-white solid
Optical Rotation
[a]D20 = 9 ± 1 ° (C=1 in CHCl3)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-a--Me-L-Arg(Pbf)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptides with specific functionalities.
  • Drug Development: In pharmaceutical research, it is used to design and optimize peptide-based drugs, enhancing their stability and bioactivity, which is crucial for developing effective therapeutics.
  • Bioconjugation: The compound is employed in bioconjugation processes, where it helps attach peptides to other biomolecules, facilitating the development of targeted drug delivery systems.
  • Research in Immunology: It is utilized in the creation of peptide vaccines, aiding in the study of immune responses and the development of immunotherapeutic strategies.
  • Protein Engineering: This chemical plays a role in modifying proteins to improve their properties, such as solubility and stability, which is essential for various applications in biotechnology and research.

Citations