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Catalog Number:
46909
CAS Number:
63264-29-9
N2-Isobutyryl-2'-O-methylguanosine
Purity:
≥ 98% (HPLC)
Synonym(s):
N2-iBu-2'-OMe-G
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Product Information

N2-Isobutyryl-2'-O-methylguanosine is a versatile nucleoside derivative that plays a significant role in biochemical research and pharmaceutical development. This compound is recognized for its unique structural features, which enhance its stability and bioavailability compared to other nucleosides. Its applications are particularly prominent in the fields of molecular biology and medicinal chemistry, where it is utilized as a building block for the synthesis of modified RNA and DNA molecules. Researchers have found that N2-Isobutyryl-2'-O-methylguanosine can improve the efficacy of oligonucleotide therapeutics, making it an essential tool in the development of targeted therapies for various diseases, including cancer and viral infections.

Additionally, this compound's ability to modulate cellular processes makes it a valuable candidate for studies involving gene expression and regulation. Its favorable properties, such as increased resistance to enzymatic degradation, allow for prolonged activity in biological systems, which is crucial for therapeutic applications. By incorporating N2-Isobutyryl-2'-O-methylguanosine into research and development projects, professionals can leverage its unique benefits to advance their work in nucleic acid chemistry and drug discovery.

Synonyms
N2-iBu-2'-OMe-G
CAS Number
63264-29-9
Purity
≥ 98% (HPLC)
Molecular Formula
C15H21N5O6
Molecular Weight
367.36
MDL Number
MFCD15145297
PubChem ID
136351472
Appearance
White to off-white free flowing powder
Conditions
Store at ≤ - 20 °
General Information
Synonyms
N2-iBu-2'-OMe-G
CAS Number
63264-29-9
Purity
≥ 98% (HPLC)
Molecular Formula
C15H21N5O6
Molecular Weight
367.36
MDL Number
MFCD15145297
PubChem ID
136351472
Appearance
White to off-white free flowing powder
Conditions
Store at ≤ - 20 °
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N2-Isobutyryl-2'-O-methylguanosine is widely utilized in research focused on:

  • Nucleotide Synthesis: This compound serves as a key building block in the synthesis of modified nucleotides, which are essential for developing new RNA-based therapeutics and diagnostics.
  • Drug Development: It plays a significant role in pharmaceutical research, particularly in designing antiviral drugs that target RNA viruses, enhancing the efficacy of treatments.
  • Biochemical Studies: Researchers use it to study RNA interactions and modifications, providing insights into cellular processes and potential disease mechanisms.
  • Gene Expression Analysis: The compound is employed in assays to analyze gene expression, helping scientists understand how genes are regulated in various conditions.
  • Therapeutic Applications: Its unique structure allows for the development of novel therapeutic agents that can improve the delivery and stability of RNA molecules in therapeutic contexts.

Citations