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Catalog Number:
46595
CAS Number:
40949-94-8
Potassium bis(trimethylsilyl)amide solution, 20% in THF
Purity:
19 - 21% (Assay)
Synonym(s):
Hexamethyldisilazane potassium salt solution, Potassium hexamethyldisilazide solution
Hazmat
Documents
$60.00 /100G
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Product Information

Potassium bis(trimethylsilyl)amide solution, 1 M in THF, is a highly versatile reagent widely utilized in organic synthesis and materials science. This compound serves as a powerful base and nucleophile, making it an essential tool for researchers and industry professionals engaged in the development of novel compounds. Its unique structure allows for effective deprotonation reactions, enabling the formation of various organometallic intermediates. This solution is particularly valuable in the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals, where precision and reactivity are paramount.

In addition to its synthetic applications, Potassium bis(trimethylsilyl)amide is also employed in the preparation of silicon-containing materials and polymers, showcasing its relevance in the field of materials science. Its compatibility with a range of substrates and solvents enhances its utility in diverse chemical processes. Researchers appreciate its stability and ease of handling, making it a preferred choice for laboratory applications. With its broad applicability and efficiency, this compound stands out as a key reagent for advancing chemical research and development.

Synonyms
Hexamethyldisilazane potassium salt solution, Potassium hexamethyldisilazide solution
CAS Number
40949-94-8
Purity
19 - 21% (Assay)
Molecular Formula
C6H18KNSi2
Molecular Weight
0
MDL Number
MFCD00010330
PubChem ID
3251421
Density
0.915 g/mL at 25 °C (Lit.)
Appearance
Colorless to amber liquid
Conditions
Store at RT
General Information
Synonyms
Hexamethyldisilazane potassium salt solution, Potassium hexamethyldisilazide solution
CAS Number
40949-94-8
Purity
19 - 21% (Assay)
Molecular Formula
C6H18KNSi2
Molecular Weight
0
MDL Number
MFCD00010330
PubChem ID
3251421
Density
0.915 g/mL at 25 °C (Lit.)
Appearance
Colorless to amber liquid
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Potassium bis(trimethylsilyl)amide solution, 1 M in THF is widely utilized in research focused on:

  • Organic Synthesis: This compound acts as a strong base in organic reactions, facilitating the deprotonation of weak acids. It's particularly useful in creating complex organic molecules, which are essential in pharmaceuticals and agrochemicals.
  • Metalation Reactions: It is employed in metalation processes, where it helps in the introduction of metal centers into organic frameworks. This is crucial in developing new catalysts and materials in the chemical industry.
  • Polymer Chemistry: The solution is used in the synthesis of silicon-containing polymers, enhancing their thermal stability and mechanical properties. This application is vital in industries producing high-performance materials.
  • Research in Nanotechnology: It serves as a precursor for the synthesis of silicon-based nanomaterials, which are increasingly important in electronics and energy storage solutions.
  • Pharmaceutical Development: The compound is utilized in the synthesis of various pharmaceutical intermediates, allowing for the efficient production of active ingredients with improved efficacy and reduced side effects.

Citations