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Catalog Number:
46580
CAS Number:
1418022-26-0
Fmoc-Val-(Dmb)Gly-OH
Purity:
≥ 95% (HPLC)
Synonym(s):
N-α-Fmoc-L-valyl-N-α-(2,4-dimethoxybenzyl)-glycine
Documents
$110.70 /100MG
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Product Information

Fmoc-Val-(Dmb)Gly-OH is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during solid-phase peptide synthesis. The presence of the 2,4-dimethoxyphenylmethyl (Dmb) group enhances its stability and solubility, making it an ideal choice for researchers focused on synthesizing complex peptides with high purity and yield.

In practical applications, Fmoc-Val-(Dmb)Gly-OH serves as a building block in the creation of bioactive peptides, which are crucial in pharmaceuticals and biotechnology. Its unique structure allows for the introduction of specific functionalities, enabling the development of targeted therapies and novel drug candidates. Researchers in the fields of medicinal chemistry and biochemistry will find this compound invaluable for its efficiency in facilitating the synthesis of peptides that can modulate biological processes, offering significant advantages over traditional methods.

Synonyms
N-α-Fmoc-L-valyl-N-α-(2,4-dimethoxybenzyl)-glycine
CAS Number
1418022-26-0
Purity
≥ 95% (HPLC)
Molecular Formula
C31H34N2O7
Molecular Weight
546.61
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -40 to -33 ° (C=1 in MeOH) (Lit.)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
N-α-Fmoc-L-valyl-N-α-(2,4-dimethoxybenzyl)-glycine
CAS Number
1418022-26-0
Purity
≥ 95% (HPLC)
Molecular Formula
C31H34N2O7
Molecular Weight
546.61
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -40 to -33 ° (C=1 in MeOH) (Lit.)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Val-(Dmb)Gly-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing researchers to create complex peptide sequences efficiently.
  • Drug Development: Its application in drug design helps in developing peptide-based therapeutics, which can lead to more effective treatments with fewer side effects compared to traditional small-molecule drugs.
  • Bioconjugation: The compound can be used in bioconjugation processes, facilitating the attachment of peptides to various biomolecules, enhancing the specificity and efficacy of targeted therapies.
  • Research in Protein Engineering: It is valuable in protein engineering studies, enabling scientists to modify protein structures and functions, which is crucial for understanding biological processes and developing new biotechnologies.
  • Diagnostics: Fmoc-Val-(Dmb)Gly-OH can be employed in the development of diagnostic tools, particularly in assays that require specific peptide interactions, improving the accuracy of disease detection.

Citations