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Catalog Number:
46308
CAS Number:
50824-05-0
4-(Trifluoromethoxy)benzyl bromide
Purity:
≥ 98% (GC)
Synonym(s):
α-Bromo-4-(trifluoromethoxy)toluene
Hazmat
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Product Information

4-(Trifluoromethoxy)benzyl bromide is a versatile chemical compound widely utilized in organic synthesis and pharmaceutical research. This compound, characterized by its trifluoromethoxy group, offers unique reactivity that makes it an excellent building block for the development of various fluorinated organic molecules. Its bromomethyl functionality allows for straightforward substitution reactions, facilitating the introduction of diverse functional groups. Researchers and industry professionals often leverage this compound in the synthesis of agrochemicals, pharmaceuticals, and advanced materials, where the incorporation of fluorine can enhance biological activity and improve compound stability.

The trifluoromethoxy group not only contributes to the compound's distinctive properties but also enhances its lipophilicity, making it particularly valuable in drug design and development. Its ability to modulate the physicochemical properties of target molecules can lead to improved efficacy and reduced toxicity. As a result, 4-(Trifluoromethoxy)benzyl bromide stands out as a crucial reagent in the toolkit of chemists aiming to innovate in the fields of medicinal chemistry and materials science.

Synonyms
α-Bromo-4-(trifluoromethoxy)toluene
CAS Number
50824-05-0
Purity
≥ 98% (GC)
Molecular Formula
C8H6BrF3O
Molecular Weight
255.03
MDL Number
MFCD00061238
PubChem ID
142785
Melting Point
22 - 24 °C
Density
1.58
Appearance
White or colorless to light yellow powder to lump to clear liquid
Boiling Point
79 °C/9 mmHg
Refractive Index
n20D 1.48
Conditions
Store at RT
General Information
Synonyms
α-Bromo-4-(trifluoromethoxy)toluene
CAS Number
50824-05-0
Purity
≥ 98% (GC)
Molecular Formula
C8H6BrF3O
Molecular Weight
255.03
MDL Number
MFCD00061238
PubChem ID
142785
Melting Point
22 - 24 °C
Density
1.58
Appearance
White or colorless to light yellow powder to lump to clear liquid
Boiling Point
79 °C/9 mmHg
Refractive Index
n20D 1.48
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-(Trifluoromethoxy)benzyl bromide is widely utilized in research focused on:

  • Synthesis of Pharmaceuticals: This compound serves as a key intermediate in the synthesis of various pharmaceutical agents, enhancing the development of new medications.
  • Fluorinated Compounds: It is used in the production of fluorinated organic compounds, which are important in agrochemicals and specialty chemicals, providing unique properties like increased stability and bioactivity.
  • Material Science: The compound is applied in the development of advanced materials, including polymers and coatings, due to its unique trifluoromethoxy group that imparts desirable chemical resistance.
  • Research in Organic Chemistry: It is a valuable reagent for organic chemists, facilitating various coupling reactions that are essential for constructing complex molecular architectures.
  • Biochemical Applications: This chemical plays a role in the design of probes and markers for biological studies, aiding in the understanding of cellular processes and interactions.

Citations