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Catalog Number:
45347
CAS Number:
403-43-0
4-Fluorobenzoyl chloride
Purity:
≥ 97% (Assay by titration)
Hazmat
Documents
$57.40 /25G
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Product Information

4-Fluorobenzoyl chloride is a versatile chemical compound widely utilized in organic synthesis and pharmaceutical research. This acyl chloride is recognized for its reactivity, particularly in acylation reactions, making it an essential building block for the synthesis of various fluorinated aromatic compounds. Its unique fluorine substituent enhances the compound's lipophilicity and biological activity, which is particularly beneficial in the development of pharmaceuticals and agrochemicals. Researchers often leverage 4-Fluorobenzoyl chloride in the preparation of fluorinated amides and esters, which are crucial intermediates in drug discovery and development.

In addition to its applications in pharmaceuticals, 4-Fluorobenzoyl chloride is also employed in the production of specialty chemicals and materials. Its ability to introduce a fluorine atom into organic molecules can significantly alter their physical and chemical properties, leading to enhanced performance in various applications. This compound is particularly valuable in the synthesis of advanced materials, where fluorination can improve thermal stability and chemical resistance. With its broad range of applications and unique properties, 4-Fluorobenzoyl chloride stands out as a key reagent for researchers and industry professionals alike.

CAS Number
403-43-0
Purity
≥ 97% (Assay by titration)
Molecular Formula
C7H4ClFO
Molecular Weight
0
MDL Number
MFCD00000684
PubChem ID
67879
Melting Point
10 °C
Density
1.32
Appearance
Colorless to light yellow to light orange clear liquid
Boiling Point
193 °C
Refractive Index
n20D 1.53
Conditions
Store at 2 - 8 °C
General Information
CAS Number
403-43-0
Purity
≥ 97% (Assay by titration)
Molecular Formula
C7H4ClFO
Molecular Weight
0
MDL Number
MFCD00000684
PubChem ID
67879
Melting Point
10 °C
Density
1.32
Appearance
Colorless to light yellow to light orange clear liquid
Boiling Point
193 °C
Refractive Index
n20D 1.53
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Fluorobenzoyl chloride is widely utilized in research focused on:

  • Synthesis of Pharmaceuticals: This compound serves as a key intermediate in the production of various pharmaceuticals, enabling the development of effective medications with enhanced therapeutic properties.
  • Organic Synthesis: It is commonly used in organic chemistry for acylation reactions, allowing researchers to create complex molecules efficiently, which is essential in drug discovery and development.
  • Polymer Chemistry: The compound is applied in the synthesis of specialty polymers, contributing to the creation of materials with unique properties for use in coatings, adhesives, and other industrial applications.
  • Fluorinated Compounds: It plays a significant role in the preparation of fluorinated compounds, which are valuable in various fields, including agrochemicals and materials science, due to their improved stability and performance.
  • Analytical Chemistry: 4-Fluorobenzoyl chloride is utilized in the derivatization of analytes for enhanced detection in chromatography, providing researchers with more accurate and reliable results in their studies.

Citations