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Catalog Number:
45300
CAS Number:
400-38-4
Isopropyl trifluoroacetate
Purity:
≥ 98% (GC)
Synonym(s):
Trifluoroacetic acid isopropyl ester
Hazmat
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Product Information

Isopropyl trifluoroacetate is a versatile chemical compound known for its unique trifluoroacetate group, which enhances its reactivity and solubility in various organic solvents. This compound is widely utilized in the synthesis of pharmaceuticals and agrochemicals, serving as an important intermediate in the production of various bioactive molecules. Its ability to act as a trifluoromethylating agent makes it particularly valuable in medicinal chemistry, where it can facilitate the introduction of trifluoromethyl groups into organic compounds, potentially improving their biological activity and metabolic stability.

In addition to its applications in drug development, Isopropyl trifluoroacetate is also employed in the field of materials science, where it can be used to modify polymer properties or as a reagent in organic synthesis. Researchers appreciate its stability and ease of handling, making it a preferred choice for laboratory applications. With its broad range of uses and significant advantages over similar compounds, Isopropyl trifluoroacetate stands out as a key player in advancing chemical research and industrial applications.

Synonyms
Trifluoroacetic acid isopropyl ester
CAS Number
400-38-4
Purity
≥ 98% (GC)
Molecular Formula
C5H7F3O2
Molecular Weight
156.1
MDL Number
MFCD00013566
PubChem ID
78998
Melting Point
-78 °C
Density
1.12
Appearance
Colorless to almost colorless clear liquid
Boiling Point
73 °C
Refractive Index
n20D 1.32
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Trifluoroacetic acid isopropyl ester
CAS Number
400-38-4
Purity
≥ 98% (GC)
Molecular Formula
C5H7F3O2
Molecular Weight
156.1
MDL Number
MFCD00013566
PubChem ID
78998
Melting Point
-78 °C
Density
1.12
Appearance
Colorless to almost colorless clear liquid
Boiling Point
73 °C
Refractive Index
n20D 1.32
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Isopropyl trifluoroacetate is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile reagent in the synthesis of various organic molecules, enabling chemists to create complex structures efficiently.
  • Fluorinated Compounds Production: It is crucial in producing fluorinated compounds, which are valuable in pharmaceuticals and agrochemicals, enhancing their efficacy and stability.
  • Solvent Applications: Isopropyl trifluoroacetate acts as a solvent in various chemical reactions, providing a medium that can dissolve a wide range of substances, thus improving reaction outcomes.
  • Analytical Chemistry: This compound is used in analytical methods, such as chromatography, helping researchers separate and identify components in complex mixtures effectively.
  • Polymer Chemistry: It plays a role in the development of fluorinated polymers, which are known for their unique properties, including chemical resistance and thermal stability, making them suitable for high-performance applications.

Citations