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Catalog Number:
45223
CAS Number:
7387-69-1
N-Benzyl-2,2,2-trifluoroacetamide
Purity:
≥ 95% (GC)
Documents
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Product Information

N-Benzyl-2,2,2-trifluoroacetamide is a versatile compound known for its unique trifluoroacetamide functional group, which enhances its reactivity and solubility in various organic solvents. This compound is particularly valuable in the synthesis of pharmaceuticals and agrochemicals, where its ability to act as a protecting group for amines is crucial. Researchers often utilize N-Benzyl-2,2,2-trifluoroacetamide in the development of new drug formulations, as it can improve the stability and bioavailability of active pharmaceutical ingredients.

Additionally, its application extends to the field of organic synthesis, where it serves as an intermediate in the preparation of complex molecules. The trifluoromethyl group imparts distinctive electronic properties, making it an attractive choice for chemists looking to optimize reaction conditions and yields. With its broad range of applications and benefits, N-Benzyl-2,2,2-trifluoroacetamide stands out as a key compound for professionals in research and industry, facilitating advancements in chemical synthesis and product development.

CAS Number
7387-69-1
Purity
≥ 95% (GC)
Molecular Formula
C9H8F3NO
Molecular Weight
203.16
MDL Number
MFCD00188542
PubChem ID
230121
Melting Point
70 - 74 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at RT
General Information
CAS Number
7387-69-1
Purity
≥ 95% (GC)
Molecular Formula
C9H8F3NO
Molecular Weight
203.16
MDL Number
MFCD00188542
PubChem ID
230121
Melting Point
70 - 74 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-Benzyl-2,2,2-trifluoroacetamide is widely utilized in research focused on:

  • Synthesis of Fluorinated Compounds: This chemical serves as a key intermediate in the synthesis of various fluorinated organic compounds, which are important in pharmaceuticals and agrochemicals.
  • Drug Development: Its unique trifluoroacetyl group enhances the bioactivity of certain drug candidates, making it valuable in medicinal chemistry for developing more effective therapeutics.
  • Analytical Chemistry: Used as a derivatizing agent in gas chromatography, it improves the detection of amines and other functional groups, aiding in the analysis of complex mixtures.
  • Material Science: This compound can be incorporated into polymer formulations to enhance thermal stability and chemical resistance, beneficial for developing advanced materials.
  • Surface Modification: It is applied in modifying surfaces to improve hydrophobicity and chemical resistance, which is useful in coatings and protective layers in various industries.

Citations