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Catalog Number:
45217
CAS Number:
404-24-0
2,2,2-Trifluoro-N-phenylacetamide
Purity:
≥ 98% (GC)
Synonym(s):
2,2,2-Trifluoroacetanilide
Documents
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Product Information

2,2,2-Trifluoro-N-phenylacetamide is a versatile compound recognized for its unique trifluoromethyl group, which enhances its chemical stability and reactivity. This compound is particularly valuable in the pharmaceutical industry, where it serves as an important intermediate in the synthesis of various biologically active molecules. Its ability to modify the electronic properties of the parent structure makes it a preferred choice for researchers aiming to develop new drugs with improved efficacy and reduced side effects. Additionally, 2,2,2-Trifluoro-N-phenylacetamide is utilized in agrochemical formulations, where its properties contribute to the development of more effective pesticides and herbicides.

The compound's distinctive trifluoromethyl group not only increases lipophilicity but also enhances metabolic stability, making it an attractive option for medicinal chemists. Its applications extend to materials science, where it can be used in the development of advanced polymers and coatings. With its broad range of applications and benefits, 2,2,2-Trifluoro-N-phenylacetamide stands out as a crucial building block for innovative solutions in various industries.

Synonyms
2,2,2-Trifluoroacetanilide
CAS Number
404-24-0
Purity
≥ 98% (GC)
Molecular Formula
C8H6F3NO
Molecular Weight
189.14
MDL Number
MFCD00196027
PubChem ID
67881
Melting Point
86 - 90 °C
Density
1.36
Appearance
White to orange to green powder to crystal
Refractive Index
n20D 1.50
Conditions
Store at RT
General Information
Synonyms
2,2,2-Trifluoroacetanilide
CAS Number
404-24-0
Purity
≥ 98% (GC)
Molecular Formula
C8H6F3NO
Molecular Weight
189.14
MDL Number
MFCD00196027
PubChem ID
67881
Melting Point
86 - 90 °C
Density
1.36
Appearance
White to orange to green powder to crystal
Refractive Index
n20D 1.50
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2,2,2-Trifluoro-N-phenylacetamide is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-inflammatory and analgesic medications.
  • Material Science: It is employed in creating fluorinated polymers, which exhibit enhanced thermal stability and chemical resistance, making them ideal for high-performance applications.
  • Agricultural Chemicals: The compound is used in formulating agrochemicals, contributing to the development of effective herbicides and pesticides that are crucial for crop protection.
  • Analytical Chemistry: It acts as a reagent in analytical methods, aiding in the detection and quantification of various substances in complex mixtures, thus enhancing research accuracy.
  • Fluorine Chemistry Research: Researchers utilize this compound to explore new fluorinated derivatives, which can lead to innovative applications in drug design and materials engineering.

Citations