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Catalog Number:
43849
CAS Number:
122684-33-7
Methyl 1-(tert-butoxycarbonyl)-3-pyrrolidinecarboxylate
Purity:
≥ 98% (GC)
Synonym(s):
Methyl 1-Boc-3-pyrrolidinecarboxylate, 1-(tert-Butoxycarbonyl)-3-pyrrolidinecarboxylic acid methylester, 1-Boc-3-pyrrolidinecarboxylic acid methyl ester, 1-tert-Butyl 3-methyl pyrrolidine-1,3-dicarboxylate
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Product Information

Methyl 1-(tert-butoxycarbonyl)-3-pyrrolidinecarboxylate is a versatile compound widely utilized in organic synthesis and pharmaceutical research. This compound, also known as Methyl 3-(Boc)-pyrrolidine-1-carboxylate, serves as a key intermediate in the synthesis of various bioactive molecules, particularly in the development of peptide-based drugs. Its unique structure allows for the introduction of functional groups that enhance the pharmacological properties of target compounds, making it invaluable in medicinal chemistry.

Researchers appreciate the compound's stability and ease of handling, which facilitate its incorporation into complex synthetic pathways. Methyl 1-(tert-butoxycarbonyl)-3-pyrrolidinecarboxylate is particularly beneficial in the synthesis of pyrrolidine derivatives, which are known for their diverse biological activities, including anti-inflammatory and analgesic effects. Its application extends to the production of agrochemicals and other specialty chemicals, showcasing its broad relevance across multiple industries.

Synonyms
Methyl 1-Boc-3-pyrrolidinecarboxylate, 1-(tert-Butoxycarbonyl)-3-pyrrolidinecarboxylic acid methylester, 1-Boc-3-pyrrolidinecarboxylic acid methyl ester, 1-tert-Butyl 3-methyl pyrrolidine-1,3-dicarboxylate
CAS Number
122684-33-7
Purity
≥ 98% (GC)
Molecular Formula
C11H19NO4
Molecular Weight
229.28
MDL Number
MFCD04038683
PubChem ID
4572775
Density
1.08
Appearance
Colorless to light orange to yellow clear liquid
Boiling Point
105 °C/0.2 mmHg
Refractive Index
n20D 1.46
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Methyl 1-Boc-3-pyrrolidinecarboxylate, 1-(tert-Butoxycarbonyl)-3-pyrrolidinecarboxylic acid methylester, 1-Boc-3-pyrrolidinecarboxylic acid methyl ester, 1-tert-Butyl 3-methyl pyrrolidine-1,3-dicarboxylate
CAS Number
122684-33-7
Purity
≥ 98% (GC)
Molecular Formula
C11H19NO4
Molecular Weight
229.28
MDL Number
MFCD04038683
PubChem ID
4572775
Density
1.08
Appearance
Colorless to light orange to yellow clear liquid
Boiling Point
105 °C/0.2 mmHg
Refractive Index
n20D 1.46
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Methyl 1-(tert-butoxycarbonyl)-3-pyrrolidinecarboxylate is widely utilized in research focused on:

  • Synthetic Organic Chemistry: This compound serves as a versatile building block in the synthesis of various pharmaceuticals and agrochemicals, enabling researchers to develop new compounds with desired biological activities.
  • Peptide Synthesis: It is commonly used in the protection of amino acids during peptide synthesis, allowing for the selective modification of specific functional groups without affecting others.
  • Drug Development: The compound plays a crucial role in the formulation of drug candidates, particularly in enhancing solubility and bioavailability, which are critical factors in effective medication.
  • Material Science: Its properties make it valuable in the development of polymers and materials with specific characteristics, such as improved thermal stability and mechanical strength.
  • Research Laboratories: It is frequently used in academic and industrial labs for various experimental protocols, providing researchers with a reliable reagent for diverse applications.

Citations