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Catalog Number:
42952
CAS Number:
129378-52-5
2-(tert-Butyldimethylsilyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide
Purity:
≥ 97% (GC)
Synonym(s):
1-(Dimethylsulfamoyl)-2-(tert-butyldimethylsilyl)-1H-imidazole
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Product Information

2-(tert-Butyldimethylsilyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide is a versatile compound widely utilized in various fields, particularly in organic synthesis and pharmaceutical research. This compound features a unique silyl protecting group, which enhances its stability and reactivity, making it an excellent choice for researchers looking to manipulate imidazole derivatives. Its sulfonamide functionality contributes to its solubility in polar solvents, facilitating its use in diverse chemical reactions, including coupling and cross-coupling processes.

In the pharmaceutical industry, this compound serves as a valuable intermediate in the synthesis of bioactive molecules, particularly those targeting specific biological pathways. Its ability to act as a protecting group for amines and other functional groups allows for selective reactions, streamlining synthetic routes. Researchers appreciate its compatibility with various reagents and conditions, which broadens its applicability in drug discovery and development. With its unique properties, 2-(tert-Butyldimethylsilyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide stands out as a crucial tool for advancing chemical research and innovation.

Synonyms
1-(Dimethylsulfamoyl)-2-(tert-butyldimethylsilyl)-1H-imidazole
CAS Number
129378-52-5
Purity
≥ 97% (GC)
Molecular Formula
C11H23N3O2SSi
Molecular Weight
289.47
MDL Number
MFCD12963638
PubChem ID
6420209
Melting Point
62 - 66 °C
Appearance
White to almost white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-(Dimethylsulfamoyl)-2-(tert-butyldimethylsilyl)-1H-imidazole
CAS Number
129378-52-5
Purity
≥ 97% (GC)
Molecular Formula
C11H23N3O2SSi
Molecular Weight
289.47
MDL Number
MFCD12963638
PubChem ID
6420209
Melting Point
62 - 66 °C
Appearance
White to almost white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-(tert-Butyldimethylsilyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a valuable intermediate in the synthesis of various pharmaceutical agents, particularly in the development of drugs targeting neurological disorders.
  • Catalysis: It is employed as a catalyst in organic reactions, enhancing reaction rates and selectivity, which is crucial in the production of fine chemicals and agrochemicals.
  • Material Science: The compound is used in the formulation of advanced materials, particularly in creating silicone-based polymers that exhibit superior thermal and chemical resistance.
  • Analytical Chemistry: It acts as a derivatizing agent in analytical techniques, improving the detection and quantification of various analytes in complex mixtures.
  • Biotechnology: This chemical is utilized in the development of biosensors, providing enhanced stability and sensitivity for detecting biological molecules.

Citations