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Catalog Number:
42548
CAS Number:
478706-39-7
(R)-Fmoc-2-amino-tetradecanoic acid
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
(2R)-2-(Fmoc-amino)tetradecanoic acid, Fmoc-D-2Ated-OH, (R)-N-(9-Fluorenylmethyloxycarbonyl)-2-amino-tetradecanoicacid
Documents
$72.31 /5MG
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Product Information

(R)-Fmoc-2-amino-tetradecanoic acid is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its long aliphatic chain enhances hydrophobic interactions, making it particularly valuable in the design of membrane-active peptides and bioactive compounds. Researchers in the fields of biochemistry and pharmaceuticals can leverage this compound for the development of novel therapeutic agents, as it facilitates the incorporation of hydrophobic residues into peptides, thereby improving their stability and bioavailability.

In addition to its applications in peptide synthesis, (R)-Fmoc-2-amino-tetradecanoic acid is also significant in the study of lipid bilayers and membrane proteins, providing insights into their structure and function. Its unique properties make it an excellent choice for researchers looking to explore the interactions between peptides and lipid environments, paving the way for advancements in drug delivery systems and therapeutic formulations.

Synonyms
(2R)-2-(Fmoc-amino)tetradecanoic acid, Fmoc-D-2Ated-OH, (R)-N-(9-Fluorenylmethyloxycarbonyl)-2-amino-tetradecanoicacid
CAS Number
478706-39-7
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C29H39NO4
Molecular Weight
465.62
MDL Number
MFCD08275905
PubChem ID
2756197
Melting Point
107 - 111 °C
Appearance
White powder
Optical Rotation
[a]D20 = 9 ± 1 ° (C=1 in DMF)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(2R)-2-(Fmoc-amino)tetradecanoic acid, Fmoc-D-2Ated-OH, (R)-N-(9-Fluorenylmethyloxycarbonyl)-2-amino-tetradecanoicacid
CAS Number
478706-39-7
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C29H39NO4
Molecular Weight
465.62
MDL Number
MFCD08275905
PubChem ID
2756197
Melting Point
107 - 111 °C
Appearance
White powder
Optical Rotation
[a]D20 = 9 ± 1 ° (C=1 in DMF)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-Fmoc-2-amino-tetradecanoic acid is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without unwanted side reactions. Its stability under various conditions makes it a preferred choice for chemists.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs, enhancing bioavailability and specificity. This can lead to more effective treatments with fewer side effects.
  • Bioconjugation: The compound is instrumental in bioconjugation processes, linking peptides to other biomolecules. This is crucial in developing targeted therapies and diagnostics in the biomedical field.
  • Research in Neuroscience: It is applied in studies related to neuropeptides, helping researchers understand neurological functions and disorders, which can lead to new therapeutic strategies.
  • Cosmetic Formulations: The compound is explored in the cosmetic industry for its potential in skin care products, where peptides can promote skin health and rejuvenation.

Citations