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Catalog Number:
42452
CAS Number:
511296-88-1
Cyclic pifithrin-α hydrobromide
Purity:
≥ 98% (HPLC)
Synonym(s):
2-(p-Tolyl)-5,6,7,8-tetrahydroimidazo[2,1-b]benzothiazolehydrobromide
Documents
$361.24 /20MG
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Product Information

Cyclic pifithrin-a hydrobromide is a potent compound recognized for its unique ability to inhibit p53-mediated transcription, making it a valuable tool in cancer research and therapeutic development. This compound is particularly significant in studies focusing on the modulation of cellular responses to stress and apoptosis, providing researchers with insights into tumor biology and potential treatment strategies. Its hydrobromide form enhances solubility, facilitating its use in various biological assays and experiments.

In practical applications, cyclic pifithrin-a hydrobromide has been employed in studies investigating the effects of p53 inhibition on cancer cell proliferation and survival, offering a pathway for developing novel anticancer therapies. Additionally, its role in understanding the mechanisms of drug resistance in tumors highlights its relevance in the pharmaceutical industry. Researchers and industry professionals can leverage this compound to explore innovative approaches in cancer treatment, making it an essential addition to any laboratory focused on oncology and molecular biology.

Synonyms
2-(p-Tolyl)-5,6,7,8-tetrahydroimidazo[2,1-b]benzothiazolehydrobromide
CAS Number
511296-88-1
Purity
≥ 98% (HPLC)
Molecular Formula
C16H16N2S·HBr
Molecular Weight
349.29
MDL Number
MFCD02683960
PubChem ID
11515812
Appearance
White to off-white powder
Conditions
Store at ≤ -4 °C
General Information
Synonyms
2-(p-Tolyl)-5,6,7,8-tetrahydroimidazo[2,1-b]benzothiazolehydrobromide
CAS Number
511296-88-1
Purity
≥ 98% (HPLC)
Molecular Formula
C16H16N2S·HBr
Molecular Weight
349.29
MDL Number
MFCD02683960
PubChem ID
11515812
Appearance
White to off-white powder
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Cyclic pifithrin-a hydrobromide is widely utilized in research focused on:

  • Neuroprotection: This compound is studied for its potential to protect neurons from damage, making it relevant in developing treatments for neurodegenerative diseases like Alzheimer's and Parkinson's.
  • Cancer Research: It has applications in oncology, where it is investigated for its ability to inhibit cell proliferation and induce apoptosis in cancer cells, providing a pathway for new therapeutic strategies.
  • Pharmacological Studies: Researchers use this compound to explore its effects on various signaling pathways, which can lead to better understanding of drug interactions and side effects in pharmacology.
  • Stress Response Research: The chemical is also examined for its role in cellular stress responses, helping scientists develop methods to enhance cell survival under stress conditions.
  • Drug Development: Its unique properties make it a candidate for formulating new drugs, particularly in creating more effective treatments with fewer side effects compared to existing options.

Citations