Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
42217
CAS Number:
39562-70-4
Nitrendipine
Purity:
≥ 99% (Assay, on dry basis)
Synonym(s):
3-Ethyl 5-methyl2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, Ethyl methyl2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate, 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylateethyl methyl ester
Documents
$83.42 /250MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Nitrendipine is a potent calcium channel blocker widely utilized in the treatment of hypertension and angina pectoris. This compound operates by inhibiting calcium influx into vascular smooth muscle and cardiac cells, leading to vasodilation and reduced blood pressure. Its unique structure, characterized by the presence of a nitrophenyl group, enhances its efficacy and selectivity, making it a preferred choice among healthcare professionals. Nitrendipine is particularly beneficial for patients who require long-term management of high blood pressure, as it offers sustained action and minimal side effects compared to other antihypertensive agents.

In addition to its primary applications in cardiovascular health, Nitrendipine has shown promise in research settings, particularly in studies exploring its effects on vascular smooth muscle and cardiac function. Its ability to selectively target calcium channels allows for innovative approaches in treating various cardiovascular disorders. Researchers and industry professionals can leverage Nitrendipine's unique properties to develop new therapeutic strategies, making it a valuable compound in both clinical and research environments.

Synonyms
3-Ethyl 5-methyl2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, Ethyl methyl2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate, 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylateethyl methyl ester
CAS Number
39562-70-4
Purity
≥ 99% (Assay, on dry basis)
Molecular Formula
C18H20N2O6
Molecular Weight
360.37
MDL Number
MFCD00082255
PubChem ID
4507
Melting Point
157 - 161 °C
Appearance
Yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
3-Ethyl 5-methyl2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, Ethyl methyl2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate, 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylateethyl methyl ester
CAS Number
39562-70-4
Purity
≥ 99% (Assay, on dry basis)
Molecular Formula
C18H20N2O6
Molecular Weight
360.37
MDL Number
MFCD00082255
PubChem ID
4507
Melting Point
157 - 161 °C
Appearance
Yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nitrendipine is widely utilized in research focused on:

  • Cardiovascular Health: Commonly prescribed for hypertension, nitrendipine helps in relaxing blood vessels, making it effective in managing high blood pressure and reducing the risk of heart disease.
  • Pharmaceutical Development: Used in the formulation of various antihypertensive drugs, it serves as a model compound for developing new medications with improved efficacy and safety profiles.
  • Clinical Research: Investigated in clinical trials to assess its effectiveness in treating conditions like angina and heart failure, providing valuable data for healthcare professionals.
  • Drug Interaction Studies: Nitrendipine is often used to study interactions with other medications, helping researchers understand its behavior in polypharmacy scenarios.
  • Educational Purposes: Frequently included in pharmacology courses, it aids students in understanding the mechanisms of action of calcium channel blockers and their therapeutic applications.

Citations