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Catalog Number:
42201
CAS Number:
338967-87-6
Mdivi-1
Purity:
≥ 98% (HPLC)
Synonym(s):
3-(2,4-Dichloro-5-methoxyphenyl)-2-thioxo-2,3-dihydro-4(1H-quinazolinone
Documents
$134.70 /10MG
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Product Information

Mdivi-1 is a potent and selective inhibitor of Drp1 (dynamin-related protein 1), a key regulator of mitochondrial fission. This compound has garnered significant attention in the fields of cellular biology and pharmacology due to its ability to modulate mitochondrial dynamics, making it a valuable tool for researchers studying mitochondrial function and related diseases. Mdivi-1 has been shown to protect against oxidative stress and apoptosis in various cell types, highlighting its potential applications in neurodegenerative diseases, cardiovascular disorders, and cancer research.

In addition to its role in basic research, Mdivi-1's unique properties may offer therapeutic advantages in developing treatments for conditions characterized by mitochondrial dysfunction. Its specificity for Drp1 allows for targeted interventions, potentially minimizing side effects associated with broader mitochondrial inhibitors. Researchers can leverage Mdivi-1 to explore new avenues in drug development and therapeutic strategies, making it an essential compound for laboratories focused on mitochondrial biology and disease mechanisms.

Synonyms
3-(2,4-Dichloro-5-methoxyphenyl)-2-thioxo-2,3-dihydro-4(1H-quinazolinone
CAS Number
338967-87-6
Purity
≥ 98% (HPLC)
Molecular Formula
C15H10Cl2N2O2S
Molecular Weight
353.22
MDL Number
MFCD00974506
PubChem ID
3825829
Melting Point
289 °C
Appearance
White to light yellow powder
Conditions
Store at ≤ -10 °C
General Information
Synonyms
3-(2,4-Dichloro-5-methoxyphenyl)-2-thioxo-2,3-dihydro-4(1H-quinazolinone
CAS Number
338967-87-6
Purity
≥ 98% (HPLC)
Molecular Formula
C15H10Cl2N2O2S
Molecular Weight
353.22
MDL Number
MFCD00974506
PubChem ID
3825829
Melting Point
289 °C
Appearance
White to light yellow powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Mdivi-1 is widely utilized in research focused on:

  • Neuroscience: Mdivi-1 is known for its neuroprotective properties, making it valuable in studies related to neurodegenerative diseases like Alzheimer's and Parkinson's. Researchers explore its potential to reduce neuronal cell death.
  • Cancer Research: This compound has shown promise in inhibiting cancer cell proliferation. It is particularly studied for its effects on various cancer types, providing insights into novel therapeutic strategies.
  • Metabolic Disorders: Mdivi-1 is being investigated for its role in modulating mitochondrial dynamics, which can be beneficial in understanding and treating metabolic disorders such as obesity and diabetes.
  • Cardiovascular Health: The compound's ability to influence mitochondrial function is being explored in the context of heart diseases, offering potential avenues for improving cardiac health.
  • Drug Development: Mdivi-1 serves as a lead compound in the development of new drugs targeting mitochondrial dysfunction, providing a foundation for creating more effective treatments with fewer side effects.

Citations