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Catalog Number:
42172
CAS Number:
171179-06-9
PD 158780
Purity:
≥ 97% (HPLC)
Synonym(s):
4-[(3-Bromophenyl)amino]-6-(methylamino)-pyrido[3,4-d]pyridimine
Documents
$396.09 /10MG
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Product Information

PD 158780 is a potent and selective inhibitor of the protein kinase B (AKT) pathway, making it a valuable compound in cancer research and therapeutic development. This compound exhibits significant potential in the study of various cancers, particularly those characterized by aberrant AKT signaling. Researchers have utilized PD 158780 to explore its effects on cell proliferation, survival, and apoptosis, providing insights into the mechanisms of tumorigenesis and potential treatment strategies. Its unique structure, featuring a bromophenyl group and a pyrido[3,4-d]pyrimidine core, enhances its binding affinity and specificity, setting it apart from other inhibitors in the field.

In addition to its applications in oncology, PD 158780 is also being investigated for its role in metabolic disorders and neurodegenerative diseases, where AKT signaling plays a critical role. The compound's ability to modulate key cellular pathways positions it as a promising candidate for further development in targeted therapies. With its demonstrated efficacy and specificity, PD 158780 represents a significant advancement in the toolkit available to researchers and industry professionals focused on developing innovative treatments.

Synonyms
4-[(3-Bromophenyl)amino]-6-(methylamino)-pyrido[3,4-d]pyridimine
CAS Number
171179-06-9
Purity
≥ 97% (HPLC)
Molecular Formula
C14H12BrN5
Molecular Weight
330.19
MDL Number
MFCD00942160
PubChem ID
4707
Melting Point
174 - 178 °C
Appearance
White to yellow to green powder or crystals
Conditions
Store at ≤ -4 °C
General Information
Synonyms
4-[(3-Bromophenyl)amino]-6-(methylamino)-pyrido[3,4-d]pyridimine
CAS Number
171179-06-9
Purity
≥ 97% (HPLC)
Molecular Formula
C14H12BrN5
Molecular Weight
330.19
MDL Number
MFCD00942160
PubChem ID
4707
Melting Point
174 - 178 °C
Appearance
White to yellow to green powder or crystals
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

PD 158780 is widely utilized in research focused on:

  • Pharmaceutical Development: This compound plays a crucial role in the development of new medications, particularly in targeting specific cancer pathways, offering potential therapies with fewer side effects compared to traditional treatments.
  • Biochemical Research: Researchers use PD 158780 to study enzyme inhibition and signaling pathways, helping to uncover mechanisms of disease and identify new drug targets.
  • Diagnostic Applications: Its unique properties make it valuable in developing diagnostic tools for certain diseases, enhancing early detection and treatment strategies.
  • Material Science: The compound is explored for its potential in creating advanced materials, including polymers that exhibit desirable thermal and mechanical properties.
  • Academic Research: Universities and research institutions employ PD 158780 in various studies, contributing to a deeper understanding of molecular interactions and drug design.

Citations