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Catalog Number:
42170
CAS Number:
183322-45-4
PD 153035 Hydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
N-(3-Bromophenyl)-6,7-dimethoxy-4-quinazolinaminehydrochloride, 4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline hydrochloride
Hazmat
Documents
$113.87 /25MG
Pack Size Availability Price
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Product Information

PD 153035 Hydrochloride is a potent and selective inhibitor of the epidermal growth factor receptor (EGFR), making it a valuable compound in cancer research and therapeutic development. This compound is particularly relevant in studies focused on the treatment of various malignancies, including non-small cell lung cancer and head and neck cancers, where EGFR plays a critical role in tumor growth and progression. Researchers utilize PD 153035 Hydrochloride to explore its efficacy in inhibiting tumor cell proliferation and inducing apoptosis, providing insights into potential combination therapies that enhance treatment outcomes.

In addition to its applications in oncology, PD 153035 Hydrochloride serves as a crucial tool in pharmacological studies aimed at understanding the signaling pathways involved in cell growth and differentiation. Its unique ability to selectively target EGFR allows for the investigation of downstream effects in cellular processes, making it an essential compound for researchers in the fields of molecular biology and pharmacology. By incorporating PD 153035 Hydrochloride into experimental designs, scientists can develop more effective therapeutic strategies and contribute to advancements in personalized medicine.

Synonyms
N-(3-Bromophenyl)-6,7-dimethoxy-4-quinazolinaminehydrochloride, 4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline hydrochloride
CAS Number
183322-45-4
Purity
≥ 98% (HPLC)
Molecular Formula
C16H14BrN3O2·HCl
Molecular Weight
396.67
MDL Number
MFCD01074805
PubChem ID
11246488
Melting Point
265 °C (Lit.)
Appearance
White to off-white powder
Conditions
Store at ≤ -10 °C
General Information
Synonyms
N-(3-Bromophenyl)-6,7-dimethoxy-4-quinazolinaminehydrochloride, 4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline hydrochloride
CAS Number
183322-45-4
Purity
≥ 98% (HPLC)
Molecular Formula
C16H14BrN3O2·HCl
Molecular Weight
396.67
MDL Number
MFCD01074805
PubChem ID
11246488
Melting Point
265 °C (Lit.)
Appearance
White to off-white powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

PD 153035 Hydrochloride is widely utilized in research focused on:

  • Cancer Research: This compound acts as a selective inhibitor of certain receptor tyrosine kinases, making it valuable for studying tumor growth and progression in various cancer types.
  • Neuroscience: It is used to investigate the role of specific signaling pathways in neuronal function, helping researchers understand neurodegenerative diseases.
  • Pharmacology: PD 153035 Hydrochloride is employed in drug development studies to evaluate its efficacy and safety as a potential therapeutic agent.
  • Cell Biology: This compound aids in elucidating cell signaling mechanisms, providing insights into cellular responses to external stimuli.
  • Biotechnology: It is applied in the development of targeted therapies, offering a pathway for creating more effective treatments with fewer side effects compared to traditional chemotherapy.

Citations