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Catalog Number:
42157
CAS Number:
881005-91-0
4-Methylumbelliferyl-β-D-glucuronide hydrate
Purity:
≥ 99% (HPLC)
Synonym(s):
4-Methylumbelliferyl-β-D-glucopyranosiduronic acid, MUG
Documents
$451.58 /250MG
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Product Information

4-Methylumbelliferyl-b-D-glucuronide hydrate is a highly valuable compound widely utilized in biochemical research, particularly in the study of glucuronidation processes. This substrate is particularly favored for its ability to serve as a fluorogenic marker, enabling researchers to detect and quantify β-glucuronidase activity in various biological samples. Its unique structure allows for the release of a fluorescent product upon enzymatic cleavage, making it an essential tool in drug metabolism studies, toxicology, and enzyme activity assays.

In addition to its applications in research, 4-Methylumbelliferyl-b-D-glucuronide hydrate is also employed in clinical diagnostics, where it aids in the assessment of liver function and the detection of certain diseases. Its high sensitivity and specificity make it a preferred choice for researchers and industry professionals looking to obtain reliable results in their assays. Overall, this compound stands out for its practical applications in both laboratory and clinical settings, providing significant advantages over similar substrates due to its enhanced fluorescent properties.

Synonyms
4-Methylumbelliferyl-β-D-glucopyranosiduronic acid, MUG
CAS Number
881005-91-0
Purity
≥ 99% (HPLC)
Molecular Formula
C16H16O9·xH2O
Molecular Weight
352.29
MDL Number
MFCD09039280
PubChem ID
92024169
Appearance
White powder
Conditions
Store at ≤ -10 °C
General Information
Synonyms
4-Methylumbelliferyl-β-D-glucopyranosiduronic acid, MUG
CAS Number
881005-91-0
Purity
≥ 99% (HPLC)
Molecular Formula
C16H16O9·xH2O
Molecular Weight
352.29
MDL Number
MFCD09039280
PubChem ID
92024169
Appearance
White powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Methylumbelliferyl-b-D-glucuronide hydrate is widely utilized in research focused on:

  • Enzyme Activity Assays: This compound serves as a substrate for glucuronidase enzymes, allowing researchers to measure enzyme activity in various biological samples, which is crucial for drug metabolism studies.
  • Biochemical Research: It is used in studies involving glucuronidation, a key metabolic process, helping scientists understand drug interactions and the effects of various compounds on metabolism.
  • Fluorescent Probes: The compound exhibits fluorescence upon hydrolysis, making it an excellent tool for visualizing enzyme activity in live cells or tissues, enhancing the understanding of cellular processes.
  • Pharmacokinetic Studies: It aids in evaluating the pharmacokinetics of drugs by providing insights into how substances are processed in the body, which is vital for drug development and safety assessments.
  • Environmental Monitoring: This chemical can be used in assessing the presence of glucuronidated metabolites in environmental samples, contributing to studies on pollution and its effects on ecosystems.

Citations