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Catalog Number:
42123
CAS Number:
135-16-0
Tetrahydrofolic acid
Purity:
≥ 65%
Synonym(s):
5,6,7,8-Tetrahydropteroyl-L-glutamic acid, THF
Documents
$65.40 /25MG
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Product Information

Tetrahydrofolic acid, a vital derivative of folic acid, plays a crucial role in various biochemical processes, particularly in the synthesis of nucleic acids and amino acids. This compound is essential for cellular division and growth, making it particularly relevant in the fields of medicine and nutrition. Tetrahydrofolic acid is widely utilized in the pharmaceutical industry for the formulation of supplements aimed at preventing folate deficiency, which can lead to serious health issues such as anemia and neural tube defects during pregnancy. Additionally, its role as a coenzyme in metabolic pathways enhances its importance in research and clinical applications, particularly in oncology and hematology.

Researchers and industry professionals appreciate tetrahydrofolic acid for its unique ability to cross the blood-brain barrier, which is critical for neurological health. Its applications extend to the development of therapeutic agents and dietary supplements, where it supports overall health and well-being. With its high bioavailability and effectiveness, tetrahydrofolic acid stands out as a preferred choice for those looking to enhance their formulations with a reliable source of folate.

Synonyms
5,6,7,8-Tetrahydropteroyl-L-glutamic acid, THF
CAS Number
135-16-0
Purity
≥ 65%
Molecular Formula
C19H23N7O6
Molecular Weight
445.43
MDL Number
MFCD00135583
PubChem ID
135402046
Appearance
Slightly yellow to light brown powder
Conditions
Store at ≤ -10 °C
General Information
Synonyms
5,6,7,8-Tetrahydropteroyl-L-glutamic acid, THF
CAS Number
135-16-0
Purity
≥ 65%
Molecular Formula
C19H23N7O6
Molecular Weight
445.43
MDL Number
MFCD00135583
PubChem ID
135402046
Appearance
Slightly yellow to light brown powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Tetrahydrofolic acid is widely utilized in research focused on:

  • Nutritional Supplements: It plays a crucial role in dietary supplements, particularly for pregnant women, to prevent neural tube defects in developing fetuses.
  • Pharmaceutical Development: This compound is essential in the synthesis of various medications, especially those targeting folate metabolism, which is important in cancer treatment.
  • Biotechnology: In genetic engineering and molecular biology, it is used as a cofactor in enzymatic reactions, facilitating the synthesis of nucleic acids and amino acids.
  • Clinical Diagnostics: Tetrahydrofolic acid levels are measured in blood tests to diagnose deficiencies, which can lead to anemia and other health issues.
  • Food Fortification: It is added to certain food products to enhance their nutritional value, ensuring populations receive adequate folate intake.

Citations