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Catalog Number:
42100
CAS Number:
4033-27-6
Dihydrofolic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
7,8-Dihydropteroyl-L-glutamic acid, Dihydropteroyl-L-glutamic acid, FAH2
Documents
$100.00 /10MG
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Product Information

Dihydrofolic acid is a vital intermediate in the biosynthesis of folate, playing a crucial role in various biological processes, particularly in the synthesis of nucleic acids and amino acids. This compound is widely recognized for its application in the pharmaceutical industry, particularly in the formulation of medications aimed at treating folate deficiency and certain types of anemia. Researchers utilize dihydrofolic acid in studies related to cellular metabolism and genetic material synthesis, making it an essential reagent in molecular biology and biochemistry laboratories. Its unique structure allows it to act as a substrate for dihydrofolate reductase, an enzyme critical in the conversion of dihydrofolate to tetrahydrofolate, which is necessary for DNA synthesis and repair.

In addition to its pharmaceutical applications, dihydrofolic acid is also employed in the agricultural sector as a nutrient supplement to enhance plant growth and development. Its ability to support the synthesis of essential biomolecules makes it a valuable compound for improving crop yields and overall plant health. With its diverse applications in both research and industry, dihydrofolic acid stands out as a compound of significant importance, offering numerous benefits to professionals in the fields of medicine, agriculture, and biotechnology.

Synonyms
7,8-Dihydropteroyl-L-glutamic acid, Dihydropteroyl-L-glutamic acid, FAH2
CAS Number
4033-27-6
Purity
≥ 99% (HPLC)
Molecular Formula
C19H21N7O6
Molecular Weight
443.41
MDL Number
MFCD00083619
PubChem ID
135402025
Appearance
Pale brown to brown powder
Conditions
Store at ≤ -10 °C
General Information
Synonyms
7,8-Dihydropteroyl-L-glutamic acid, Dihydropteroyl-L-glutamic acid, FAH2
CAS Number
4033-27-6
Purity
≥ 99% (HPLC)
Molecular Formula
C19H21N7O6
Molecular Weight
443.41
MDL Number
MFCD00083619
PubChem ID
135402025
Appearance
Pale brown to brown powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Dihydrofolic acid is widely utilized in research focused on:

  • Pharmaceutical Development: It serves as a precursor in the synthesis of folic acid, which is essential in developing medications for treating various conditions, including anemia and certain cancers.
  • Biochemical Research: Researchers use it to study folate metabolism and its role in cellular processes, helping to understand diseases linked to folate deficiency.
  • Nutrition Science: Dihydrofolic acid is important in formulating dietary supplements aimed at preventing deficiencies, particularly in pregnant women to reduce the risk of neural tube defects in infants.
  • Microbiology: It is utilized in culture media for growing certain bacteria, allowing scientists to explore microbial metabolism and antibiotic resistance mechanisms.
  • Genetic Studies: The compound is employed in experiments related to DNA synthesis and repair, providing insights into genetic disorders and potential therapeutic targets.

Citations