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Catalog Number:
42003
CAS Number:
57360-69-7
MTT Formazan
Grade:
suitable for Hematology & Histology
Purity:
≥ 97% (TLC)
Synonym(s):
1-(4,5-Dimethylthiazol-2-yl)-3,5-diphenylformazan, Thiazolyl blue formazan
Documents
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Product Information

MTT Formazan is a vital compound widely utilized in biological and biochemical research, particularly in cell viability assays. This compound, a derivative of the widely known MTT reagent, exhibits unique properties that make it an essential tool for researchers assessing cellular metabolic activity. MTT Formazan is characterized by its vibrant color, which allows for easy spectrophotometric measurement, providing a reliable means to quantify cell proliferation and cytotoxicity. Its application extends to various fields, including pharmacology, toxicology, and cancer research, where it aids in evaluating the efficacy of new drugs and treatments.

Researchers appreciate MTT Formazan for its stability and ease of use, making it a preferred choice for high-throughput screening assays. The compound's ability to form a colored formazan product upon reduction by viable cells enhances its utility in diverse experimental setups. Additionally, MTT Formazan's compatibility with various cell types and its straightforward preparation process further solidify its position as a go-to reagent in laboratories worldwide.

Synonyms
1-(4,5-Dimethylthiazol-2-yl)-3,5-diphenylformazan, Thiazolyl blue formazan
CAS Number
57360-69-7
Purity
≥ 97% (TLC)
Grade
suitable for Hematology & Histology
Molecular Formula
C18H17N5S
Molecular Weight
335.43
MDL Number
MFCD00080731
PubChem ID
3634887
Appearance
Very dark purple and black powder
Conditions
Store at RT
General Information
Synonyms
1-(4,5-Dimethylthiazol-2-yl)-3,5-diphenylformazan, Thiazolyl blue formazan
CAS Number
57360-69-7
Purity
≥ 97% (TLC)
Grade
suitable for Hematology & Histology
Molecular Formula
C18H17N5S
Molecular Weight
335.43
MDL Number
MFCD00080731
PubChem ID
3634887
Appearance
Very dark purple and black powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

MTT Formazan is widely utilized in research focused on:

  • Cell Viability Assays: This compound is a key reagent in colorimetric assays to assess cell viability and proliferation, allowing researchers to evaluate the effects of drugs or treatments on cell health.
  • Drug Development: In pharmaceutical research, MTT Formazan helps in screening potential drug candidates by providing insights into their cytotoxicity and therapeutic efficacy.
  • Biochemical Studies: It is used in various biochemical assays to measure metabolic activity in cells, aiding in the understanding of cellular processes and disease mechanisms.
  • Environmental Toxicology: MTT Formazan is applied in studies assessing the toxicity of environmental pollutants on microbial and plant cells, contributing to ecological risk assessments.
  • Comparative Analysis: Its advantages over similar compounds include higher sensitivity and specificity in detecting viable cells, making it a preferred choice in many laboratory settings.

Citations