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Catalog Number:
41724
Methyl-PEG24-azide
Purity:
≥ 95% (HPLC)
Synonym(s):
O-(2-Azidoethyl)-O'-methyltricosaethylene glycol, mPEG24-Azide, mPEG24-N3, 73-Azido-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71-tetracosaoxatriheptacontane
Documents
$458.09 /25MG
Pack Size Availability Price
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Product Information

Methyl-PEG24-azide is a versatile polyethylene glycol derivative that features an azide functional group, making it an invaluable tool in bioconjugation and click chemistry applications. This compound is particularly useful for researchers looking to create stable linkages between biomolecules, such as proteins, peptides, or nucleic acids, and various functional groups. Its hydrophilic nature enhances solubility in aqueous environments, facilitating its use in biological systems. Methyl-PEG24-azide is commonly employed in the development of drug delivery systems, where it can improve the pharmacokinetics of therapeutic agents by providing a stealth effect, thereby reducing immunogenicity and enhancing circulation time in the bloodstream.

Moreover, the azide group allows for selective reactions with alkyne-containing molecules through the well-known azide-alkyne cycloaddition (AAC) reaction, enabling the formation of complex bioconjugates. This property is particularly advantageous in the fields of biochemistry and molecular biology, where precise modifications of biomolecules are essential. Researchers can leverage Methyl-PEG24-azide for applications in targeted therapy, imaging, and diagnostics, making it a critical component in the advancement of innovative biomedical solutions.

Synonyms
O-(2-Azidoethyl)-O'-methyltricosaethylene glycol, mPEG24-Azide, mPEG24-N3, 73-Azido-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71-tetracosaoxatriheptacontane
Purity
≥ 95% (HPLC)
Molecular Formula
C49H99N3O24
Molecular Weight
1114.33
Appearance
White to slightly yellow powder
Conditions
Store at ≤ -4 °C
General Information
Synonyms
O-(2-Azidoethyl)-O'-methyltricosaethylene glycol, mPEG24-Azide, mPEG24-N3, 73-Azido-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71-tetracosaoxatriheptacontane
Purity
≥ 95% (HPLC)
Molecular Formula
C49H99N3O24
Molecular Weight
1114.33
Appearance
White to slightly yellow powder
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Methyl-PEG24-azide is widely utilized in research focused on:

  • Bioconjugation: This compound serves as a versatile linker in bioconjugation processes, allowing researchers to attach biomolecules like proteins or antibodies to surfaces or other molecules, enhancing the development of targeted therapies.
  • Drug Delivery Systems: Its unique properties facilitate the creation of drug delivery systems that improve the solubility and stability of therapeutic agents, making treatments more effective and reducing side effects.
  • Surface Modification: Methyl-PEG24-azide is used to modify surfaces of medical devices and implants, promoting biocompatibility and reducing protein adsorption, which is crucial for improving patient outcomes.
  • Fluorescent Labeling: This compound can be employed in fluorescent labeling techniques, enabling researchers to track and visualize biological processes in real-time, which is essential in cellular biology studies.
  • Polymer Chemistry: In polymer science, it acts as a building block for synthesizing functionalized polymers, leading to innovative materials with tailored properties for various applications, such as sensors and drug carriers.

Citations