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Catalog Number:
41716
CAS Number:
622405-78-1
Methyl-PEG4-NHS ester
Purity:
≥ 90%
Synonym(s):
N-Succinimidyl 4,7,10,13-tetraoxatetradecanoate, 4,7,10,13-Tetraoxatetradecanoic acid N-succinimidylester, mPEG4-NHS ester
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$66.80 /25MG
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Product Information

Methyl-PEG4-NHS ester is a versatile and highly functional compound widely utilized in bioconjugation and drug delivery applications. This compound features a polyethylene glycol (PEG) backbone, which enhances solubility and biocompatibility, making it ideal for use in various biomedical fields. Its NHS (N-hydroxysuccinimide) ester functionality allows for efficient coupling with amine-containing biomolecules, facilitating the formation of stable conjugates. Researchers and industry professionals leverage Methyl-PEG4-NHS ester for its ability to improve the pharmacokinetics of therapeutic agents, enhance targeted delivery, and increase the efficacy of drug formulations.

In addition to its applications in drug development, Methyl-PEG4-NHS ester is also employed in the creation of antibody-drug conjugates (ADCs) and other bioconjugates, enabling precise targeting of cancer cells while minimizing off-target effects. Its unique properties, such as increased circulation time and reduced immunogenicity, make it a preferred choice for those looking to optimize their therapeutic strategies. With its broad range of applications and benefits, Methyl-PEG4-NHS ester stands out as a valuable tool for researchers and professionals in the pharmaceutical and biotechnology sectors.

Synonyms
N-Succinimidyl 4,7,10,13-tetraoxatetradecanoate, 4,7,10,13-Tetraoxatetradecanoic acid N-succinimidylester, mPEG4-NHS ester
CAS Number
622405-78-1
Purity
≥ 90%
Molecular Formula
C14H23NO8
Molecular Weight
333.34
MDL Number
MFCD11041112
PubChem ID
44622261
Appearance
Almost colorless clear liquid
Conditions
Store at ≤ -4 °C
General Information
Synonyms
N-Succinimidyl 4,7,10,13-tetraoxatetradecanoate, 4,7,10,13-Tetraoxatetradecanoic acid N-succinimidylester, mPEG4-NHS ester
CAS Number
622405-78-1
Purity
≥ 90%
Molecular Formula
C14H23NO8
Molecular Weight
333.34
MDL Number
MFCD11041112
PubChem ID
44622261
Appearance
Almost colorless clear liquid
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Methyl-PEG4-NHS ester is widely utilized in research focused on:

  • Bioconjugation: This compound is commonly used to attach biomolecules, such as proteins or antibodies, to surfaces or other molecules, enhancing the functionality of diagnostic and therapeutic agents.
  • Drug Delivery Systems: Its properties allow for the creation of advanced drug delivery systems, improving the solubility and stability of pharmaceuticals, which is crucial in the development of effective treatments.
  • Protein Modification: Researchers leverage this ester for modifying proteins to study their functions or to create targeted therapies, making it a valuable tool in biochemistry and molecular biology.
  • Surface Coatings: The compound is used in the development of surface coatings that improve biocompatibility, which is essential in medical device manufacturing and tissue engineering.
  • Diagnostics: Methyl-PEG4-NHS ester plays a role in the development of diagnostic assays by facilitating the immobilization of biomolecules, enhancing sensitivity and specificity in various tests.

Citations