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Catalog Number:
41698
Methyl-PEG24-maleimide
Purity:
≥ 93% (HPLC)
Synonym(s):
mPEG24-Maleimide, 3-Maleimido-N-(2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71-tetracosaoxatriheptacontan-73-yl)propionamide
Documents
$459.29 /25MG
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Product Information

Methyl-PEG24-maleimide is a versatile compound widely utilized in bioconjugation and drug delivery applications. This maleimide-functionalized polyethylene glycol (PEG) derivative offers excellent solubility and biocompatibility, making it an ideal choice for researchers looking to enhance the stability and efficacy of therapeutic agents. Its unique maleimide group allows for selective conjugation with thiol-containing biomolecules, facilitating the development of targeted drug delivery systems and diagnostic tools.

In the pharmaceutical industry, Methyl-PEG24-maleimide is particularly valuable for creating antibody-drug conjugates (ADCs) and other bioconjugates, which can improve the pharmacokinetics and reduce the toxicity of drugs. Its ability to form stable linkages with proteins and peptides enables the design of innovative therapeutics that can effectively target specific cells or tissues. Additionally, the PEG component contributes to reduced immunogenicity and enhanced circulation time in vivo, making it a preferred choice for many applications in drug development and biomedical research.

Synonyms
mPEG24-Maleimide, 3-Maleimido-N-(2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71-tetracosaoxatriheptacontan-73-yl)propionamide
Purity
≥ 93% (HPLC)
Molecular Formula
C56H106N2O27
Molecular Weight
1239.45
Appearance
White to off-white powder
Conditions
Store at ≤ -10 °C
General Information
Synonyms
mPEG24-Maleimide, 3-Maleimido-N-(2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71-tetracosaoxatriheptacontan-73-yl)propionamide
Purity
≥ 93% (HPLC)
Molecular Formula
C56H106N2O27
Molecular Weight
1239.45
Appearance
White to off-white powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Methyl-PEG24-maleimide is widely utilized in research focused on:

  • Bioconjugation: This compound is commonly used to attach biomolecules, such as proteins or antibodies, to surfaces or other molecules, enhancing the functionality of drug delivery systems.
  • Drug Delivery: Its unique properties allow for improved solubility and stability of therapeutic agents, making it ideal for formulating targeted drug delivery systems in pharmaceuticals.
  • Diagnostic Applications: Methyl-PEG24-maleimide is employed in the development of diagnostic tools, such as biosensors, where it helps in the immobilization of biomolecules for better detection sensitivity.
  • Polymer Chemistry: This compound serves as a building block in the synthesis of advanced polymers, contributing to the development of materials with tailored properties for various industrial applications.
  • Cosmetic Formulations: In the cosmetics industry, it is used to enhance the texture and stability of products, providing a smooth application and prolonged shelf life.

Citations