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Catalog Number:
41642
CAS Number:
53912-80-4
N-Benzyl-L-prolinol
Purity:
≥ 95% (GC)
Synonym(s):
(S)-1-Benzyl-2-pyrrolidinemethanol
Documents
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Product Information

N-Benzyl-L-prolinol is a versatile compound recognized for its unique structure and functional properties, making it an essential building block in organic synthesis and pharmaceutical development. This chiral amine is particularly valued in asymmetric synthesis, where it serves as a chiral auxiliary or catalyst, facilitating the production of enantiomerically pure compounds. Its ability to form stable complexes with various substrates enhances its utility in the synthesis of complex molecules, including pharmaceuticals and agrochemicals.

In addition to its role in synthesis, N-Benzyl-L-prolinol has shown potential in medicinal chemistry, particularly in the development of novel therapeutic agents. Researchers have explored its applications in the synthesis of bioactive compounds, including those targeting neurological disorders. Its favorable solubility and stability profile further contribute to its appeal in formulation development. With its diverse applications and significant advantages over similar compounds, N-Benzyl-L-prolinol stands out as a valuable resource for researchers and industry professionals seeking innovative solutions in chemical synthesis and drug development.

Synonyms
(S)-1-Benzyl-2-pyrrolidinemethanol
CAS Number
53912-80-4
Purity
≥ 95% (GC)
Molecular Formula
C12H17NO
Molecular Weight
191.27
MDL Number
MFCD00011728
PubChem ID
562951
Density
1.05 g/mL
Appearance
Light orange to yellow to green clear liquid
Boiling Point
92 °C / 0.2 mmHg (Lit.)
Refractive Index
n20D 1.54
Optical Rotation
[a]20D = -76 to -69 ° (neat)
Conditions
Store at RT
General Information
Synonyms
(S)-1-Benzyl-2-pyrrolidinemethanol
CAS Number
53912-80-4
Purity
≥ 95% (GC)
Molecular Formula
C12H17NO
Molecular Weight
191.27
MDL Number
MFCD00011728
PubChem ID
562951
Density
1.05 g/mL
Appearance
Light orange to yellow to green clear liquid
Boiling Point
92 °C / 0.2 mmHg (Lit.)
Refractive Index
n20D 1.54
Optical Rotation
[a]20D = -76 to -69 ° (neat)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-Benzyl-L-prolinol is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Asymmetric Synthesis: It is commonly used as a chiral auxiliary in asymmetric synthesis, enabling chemists to produce enantiomerically pure compounds more efficiently than traditional methods.
  • Organic Synthesis: N-Benzyl-L-prolinol plays a crucial role in organic synthesis, particularly in the formation of complex molecules, which is essential in the fields of medicinal chemistry and materials science.
  • Research in Catalysis: This compound is utilized in catalytic processes, enhancing reaction rates and selectivity, which is vital for researchers looking to optimize chemical reactions.
  • Biochemical Studies: It is also employed in biochemical research to study enzyme mechanisms and interactions, providing insights into biological processes that can lead to new therapeutic strategies.

Citations