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Catalog Number:
41566
CAS Number:
259537-92-3
(R)-2-(Aminomethyl)-1-Boc-pyrrolidine
Purity:
≥ 99% (Chiral purity)
Synonym(s):
(R)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine, tert-Butyl (R)-2-(aminomethyl)-1-pyrrolidinecarboxylate
Hazmat
Documents
$56.99 /100MG
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Product Information

(R)-2-(Aminomethyl)-1-Boc-pyrrolidine is a versatile compound widely utilized in the field of organic synthesis and pharmaceutical development. This chiral pyrrolidine derivative is particularly valued for its role as a building block in the synthesis of various bioactive molecules, including pharmaceuticals and agrochemicals. Its unique structure, featuring a tert-butoxycarbonyl (Boc) protecting group, allows for selective reactions that enhance the efficiency of synthetic pathways. Researchers appreciate its ability to facilitate the introduction of amine functionalities, making it an essential component in the development of novel therapeutic agents.

In addition to its applications in drug discovery, (R)-2-(Aminomethyl)-1-Boc-pyrrolidine is also employed in the synthesis of peptide-based compounds and as a chiral auxiliary in asymmetric synthesis. Its favorable properties, such as high stability and ease of handling, make it an attractive choice for both academic and industrial laboratories. The compound's potential to streamline complex synthetic routes while maintaining high enantioselectivity positions it as a valuable asset in the toolkit of chemists and researchers focused on innovative solutions in medicinal chemistry.

Synonyms
(R)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine, tert-Butyl (R)-2-(aminomethyl)-1-pyrrolidinecarboxylate
CAS Number
259537-92-3
Purity
≥ 99% (Chiral purity)
Molecular Formula
C10H20N2O2
Molecular Weight
0
MDL Number
MFCD03419256
PubChem ID
2756484
Appearance
Clear colorless liquid
Boiling Point
98 - 110 °C / 1mmHg
Refractive Index
n20D 1.47 (Lit.)
Optical Rotation
[á]/D = 47 ± 2 ° (C = 1 in Chloroform)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(R)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine, tert-Butyl (R)-2-(aminomethyl)-1-pyrrolidinecarboxylate
CAS Number
259537-92-3
Purity
≥ 99% (Chiral purity)
Molecular Formula
C10H20N2O2
Molecular Weight
0
MDL Number
MFCD03419256
PubChem ID
2756484
Appearance
Clear colorless liquid
Boiling Point
98 - 110 °C / 1mmHg
Refractive Index
n20D 1.47 (Lit.)
Optical Rotation
[á]/D = 47 ± 2 ° (C = 1 in Chloroform)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-2-(Aminomethyl)-1-Boc-pyrrolidine is widely utilized in research focused on:

  • Synthesis of Pharmaceuticals: This compound serves as a key intermediate in the synthesis of various pharmaceutical agents, particularly in the development of drugs targeting neurological disorders.
  • Peptide Chemistry: It is employed in peptide synthesis, acting as a protecting group for amines, which helps streamline the process of creating complex peptide structures.
  • Research in Organic Chemistry: The compound is a valuable building block in organic synthesis, allowing chemists to create diverse chemical entities with specific functional properties.
  • Drug Development: Its unique structure enhances the bioavailability of certain drugs, making it an important component in the formulation of effective therapeutic agents.
  • Material Science: This chemical is also explored in the development of new materials, particularly in creating polymers with enhanced properties for various industrial applications.

Citations