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Catalog Number:
41524
CAS Number:
22677-21-0
(R)-(+)-4-Hydroxy-2-pyrrolidinone
Purity:
≥ 96.5% (GC)
Synonym(s):
(R)-β-Hydroxy-γ-butyrolactam
Documents
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Product Information

(R)-(+)-4-Hydroxy-2-pyrrolidinone is a versatile compound recognized for its significant role in various chemical and pharmaceutical applications. This chiral building block is particularly valuable in the synthesis of bioactive molecules and pharmaceuticals, where its unique hydroxyl and pyrrolidinone functionalities enhance reactivity and selectivity. Researchers and industry professionals utilize this compound in the development of chiral catalysts, which are essential for producing enantiomerically pure compounds in asymmetric synthesis. Its ability to act as a precursor in the synthesis of amino acids and other nitrogen-containing compounds further underscores its importance in medicinal chemistry and drug development.

Moreover, (R)-(+)-4-Hydroxy-2-pyrrolidinone is noted for its stability and ease of handling, making it an attractive choice for laboratory and industrial applications. Its potential in the formulation of advanced materials and its role in the development of novel therapeutic agents highlight its relevance in cutting-edge research. With its favorable properties and diverse applications, this compound stands out as a crucial ingredient for professionals seeking innovative solutions in chemical synthesis and pharmaceutical development.

Synonyms
(R)-β-Hydroxy-γ-butyrolactam
CAS Number
22677-21-0
Purity
≥ 96.5% (GC)
Molecular Formula
C4H7NO2
Molecular Weight
101.1
MDL Number
MFCD00273364
PubChem ID
152807
Melting Point
156 - 159 °C (Lit.)
Appearance
White to off-white solid
Optical Rotation
[á]23/D = 43 ° (C = 1 in ethanol)
Conditions
Store at RT
General Information
Synonyms
(R)-β-Hydroxy-γ-butyrolactam
CAS Number
22677-21-0
Purity
≥ 96.5% (GC)
Molecular Formula
C4H7NO2
Molecular Weight
101.1
MDL Number
MFCD00273364
PubChem ID
152807
Melting Point
156 - 159 °C (Lit.)
Appearance
White to off-white solid
Optical Rotation
[á]23/D = 43 ° (C = 1 in ethanol)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-(+)-4-Hydroxy-2-pyrrolidinone is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Chiral Building Blocks: It is an important chiral building block in organic synthesis, allowing chemists to create enantiomerically pure compounds, which are crucial for the efficacy of many drugs.
  • Biochemical Research: Researchers use this compound to study its effects on biological systems, helping to understand metabolic pathways and enzyme interactions.
  • Polymer Chemistry: It can be utilized in the formulation of biodegradable polymers, contributing to environmentally friendly materials that are gaining traction in various industries.
  • Cosmetic Applications: The compound is also explored for its potential in cosmetic formulations, where it may enhance skin hydration and stability of products.

Citations