Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
41352
CAS Number:
106513-42-2
Ethyl (S)-(-)-2-(tert-butyldimethylsilyloxy)propionate
Purity:
≥ 97.5% (GC)
Synonym(s):
(S)-2-(tert-Butyldimethylsilanyloxy)propionic acid ethyl ester
Hazmat
Documents
$172.36 /25ML
Pack Size Availability Price
Request Bulk Quote
Product Information

Ethyl (S)-(-)-2-(tert-butyldimethylsilyloxy)propionate is a versatile chemical compound widely utilized in organic synthesis and pharmaceutical applications. This compound is particularly valued for its role as a protecting group in the synthesis of complex molecules, allowing chemists to selectively modify functional groups without interfering with others. Its unique tert-butyldimethylsilyl (TBDMS) group provides stability and solubility, making it an ideal choice for reactions requiring high specificity and efficiency. Researchers in the fields of medicinal chemistry and materials science often leverage this compound to enhance the yield and purity of their target products.

In addition to its protective capabilities, Ethyl (S)-(-)-2-(tert-butyldimethylsilyloxy)propionate serves as a building block in the synthesis of various bioactive molecules, including pharmaceuticals and agrochemicals. Its ability to facilitate the formation of carbon-carbon bonds and its compatibility with a range of reaction conditions make it a valuable asset in both academic and industrial laboratories. By incorporating this compound into their workflows, professionals can streamline their processes, reduce waste, and achieve higher overall efficiency in their synthetic endeavors.

Synonyms
(S)-2-(tert-Butyldimethylsilanyloxy)propionic acid ethyl ester
CAS Number
106513-42-2
Purity
≥ 97.5% (GC)
Molecular Formula
C11H24O3Si
Molecular Weight
232.39
MDL Number
MFCD00192135
PubChem ID
4343488
Density
0.875 g / mL at 25 °C (Lit.)
Appearance
Colorless liquid
Boiling Point
187 °C (Lit.)
Refractive Index
n20D = 1.425 (Lit.)
Optical Rotation
[ॅ]20D = -30 +/- 1 ° (C = 1 in CHCl3)
General Information
Synonyms
(S)-2-(tert-Butyldimethylsilanyloxy)propionic acid ethyl ester
CAS Number
106513-42-2
Purity
≥ 97.5% (GC)
Molecular Formula
C11H24O3Si
Molecular Weight
232.39
MDL Number
MFCD00192135
PubChem ID
4343488
Density
0.875 g / mL at 25 °C (Lit.)
Appearance
Colorless liquid
Boiling Point
187 °C (Lit.)
Refractive Index
n20D = 1.425 (Lit.)
Optical Rotation
[ॅ]20D = -30 +/- 1 ° (C = 1 in CHCl3)
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ethyl (S)-(-)-2-(tert-butyldimethylsilyloxy)propionate is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile building block in organic chemistry, enabling researchers to create complex molecules efficiently.
  • Chiral Auxiliaries: Its chiral nature makes it valuable in asymmetric synthesis, helping chemists produce enantiomerically pure compounds, which are crucial in pharmaceuticals.
  • Protecting Groups: The tert-butyldimethylsilyl group acts as an effective protecting group for alcohols during multi-step synthesis, enhancing reaction selectivity and yield.
  • Drug Development: In medicinal chemistry, it is used to modify drug candidates, improving their solubility and stability, which is essential for effective formulations.
  • Material Science: This compound can be incorporated into polymer systems to enhance properties such as thermal stability and mechanical strength, making it useful in advanced materials applications.

Citations