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Catalog Number:
41121
CAS Number:
2129-89-7
Methyl(diphenyl)phosphine oxide
Purity:
≥ 98% (GC)
Synonym(s):
Methyldiphenylphosphine oxide, Methyldiphenyloxophosphine, Diphenylmethylphosphine oxide
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Product Information

Methyl(diphenyl)phosphine oxide is a versatile organophosphorus compound known for its significant role in various chemical applications. This compound is recognized for its ability to act as a ligand in coordination chemistry, making it invaluable in the synthesis of organometallic complexes. Its unique structure allows for enhanced stability and reactivity, which is particularly beneficial in catalysis and organic synthesis. Researchers often utilize Methyl(diphenyl)phosphine oxide in the development of phosphine oxide-based catalysts, which are essential in facilitating a range of chemical reactions, including cross-coupling reactions and polymerization processes.

In addition to its applications in catalysis, this compound is also employed in the pharmaceutical industry for the development of new drug candidates. Its properties enable the formation of stable intermediates, which can lead to the efficient synthesis of complex organic molecules. Methyl(diphenyl)phosphine oxide stands out due to its high selectivity and efficiency in reactions, making it a preferred choice for chemists seeking reliable and effective reagents in their research and industrial applications.

Synonyms
Methyldiphenylphosphine oxide, Methyldiphenyloxophosphine, Diphenylmethylphosphine oxide
CAS Number
2129-89-7
Purity
≥ 98% (GC)
Molecular Formula
C13H13OP
Molecular Weight
216.22
MDL Number
MFCD00002081
PubChem ID
75041
Melting Point
111 - 115 °C
Appearance
White to off-white crystal
Boiling Point
180 °C / 1 mmHg (Lit.)
Conditions
Store at RT
General Information
Synonyms
Methyldiphenylphosphine oxide, Methyldiphenyloxophosphine, Diphenylmethylphosphine oxide
CAS Number
2129-89-7
Purity
≥ 98% (GC)
Molecular Formula
C13H13OP
Molecular Weight
216.22
MDL Number
MFCD00002081
PubChem ID
75041
Melting Point
111 - 115 °C
Appearance
White to off-white crystal
Boiling Point
180 °C / 1 mmHg (Lit.)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Methyl(diphenyl)phosphine oxide is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile reagent in organic chemistry, facilitating the synthesis of various phosphine derivatives, which are crucial in developing pharmaceuticals and agrochemicals.
  • Catalysis: It acts as a ligand in transition metal-catalyzed reactions, enhancing reaction efficiency and selectivity, particularly in cross-coupling reactions used in the production of complex organic molecules.
  • Material Science: The compound is employed in the formulation of advanced materials, including polymers and coatings, due to its ability to improve thermal and mechanical properties.
  • Pharmaceutical Development: Its unique chemical properties make it valuable in drug discovery, particularly in designing compounds that target specific biological pathways, improving therapeutic efficacy.
  • Analytical Chemistry: Methyl(diphenyl)phosphine oxide is utilized in analytical methods for detecting and quantifying phosphine compounds, aiding in environmental monitoring and safety assessments.

Citations