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Catalog Number:
41076
CAS Number:
943757-71-9
(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol Trimethylsilyl Ether
Purity:
≥ 99.5% (Chiral purity)
Synonym(s):
(R)-(+)-2-[Diphenyl(trimethylsilyloxy)methyl]pyrrolidine, a,α-Diphenyl-D-prolinol Trimethylsilyl Ether, (R)-Hayashi-Jorgensen catalyst
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Product Information

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Trimethylsilyl Ether is a versatile compound widely utilized in organic synthesis and pharmaceutical research. This compound, recognized for its unique structural features, serves as an effective chiral auxiliary in asymmetric synthesis, enabling the production of enantiomerically pure compounds. Its trimethylsilyl ether functionality enhances its stability and solubility, making it an ideal candidate for various reactions, including nucleophilic substitutions and coupling reactions. Researchers appreciate its role in the development of complex molecules, particularly in the synthesis of biologically active compounds and intermediates in drug discovery.

In addition to its synthetic applications, this compound is also valuable in the field of materials science, where it can be employed in the formulation of advanced materials and coatings. Its ability to modify surface properties and enhance adhesion makes it a preferred choice for industries looking to improve product performance. With its broad range of applications and unique properties, (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Trimethylsilyl Ether stands out as a crucial tool for chemists and researchers aiming to innovate and optimize their processes.

Synonyms
(R)-(+)-2-[Diphenyl(trimethylsilyloxy)methyl]pyrrolidine, a,α-Diphenyl-D-prolinol Trimethylsilyl Ether, (R)-Hayashi-Jorgensen catalyst
CAS Number
943757-71-9
Purity
≥ 99.5% (Chiral purity)
Molecular Formula
C20H27NOSi
Molecular Weight
325.53
MDL Number
MFCD09265100
PubChem ID
23629008
Density
1.04 g/mL
Appearance
Pale yellow oil
Refractive Index
n20D 1.55
Optical Rotation
[a]D20 = 48 - 54 ° (C = 1 in CHCl3)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(R)-(+)-2-[Diphenyl(trimethylsilyloxy)methyl]pyrrolidine, a,α-Diphenyl-D-prolinol Trimethylsilyl Ether, (R)-Hayashi-Jorgensen catalyst
CAS Number
943757-71-9
Purity
≥ 99.5% (Chiral purity)
Molecular Formula
C20H27NOSi
Molecular Weight
325.53
MDL Number
MFCD09265100
PubChem ID
23629008
Density
1.04 g/mL
Appearance
Pale yellow oil
Refractive Index
n20D 1.55
Optical Rotation
[a]D20 = 48 - 54 ° (C = 1 in CHCl3)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol Trimethylsilyl Ether is widely utilized in research focused on:

  • Synthetic Organic Chemistry: This compound serves as a versatile reagent in the synthesis of complex organic molecules, allowing chemists to create intricate structures with high selectivity.
  • Pharmaceutical Development: It plays a crucial role in drug formulation processes, particularly in enhancing the solubility and stability of active pharmaceutical ingredients, which is vital for effective medication delivery.
  • Material Science: The compound is used in the development of advanced materials, including polymers and coatings, that require specific chemical properties for improved performance and durability.
  • Analytical Chemistry: It acts as a derivatizing agent in chromatography, helping to improve the detection and quantification of various analytes, which is essential for quality control in laboratories.
  • Biotechnology: This chemical is utilized in the modification of biomolecules, aiding in the development of bioconjugates for targeted drug delivery systems, thus enhancing therapeutic efficacy.

Citations