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Catalog Number:
40889
CAS Number:
20439-47-8
1R,2R-(-)-1,2-Cyclohexanediamine
Purity:
≥ 98% (GC)
Synonym(s):
(1R-(-)-trans-1,2-Diaminocyclohexane
Hazmat
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Product Information

(1R,2R)-(-)-1,2-Cyclohexanediamine is a versatile chiral diamine widely utilized in the synthesis of various pharmaceuticals and fine chemicals. Its unique stereochemistry allows it to serve as an essential building block in asymmetric synthesis, particularly in the production of chiral ligands and catalysts. This compound is particularly valued in the development of enantiomerically pure compounds, which are crucial in the pharmaceutical industry for creating effective and safe medications. Additionally, (1R,2R)-(-)-1,2-Cyclohexanediamine is employed in the preparation of polyamides and other polymers, enhancing material properties and performance in various applications.

Researchers and industry professionals appreciate (1R,2R)-(-)-1,2-Cyclohexanediamine for its ability to facilitate complex chemical transformations with high selectivity. Its application extends to the production of agrochemicals and specialty chemicals, where it contributes to the development of innovative solutions. With its favorable reactivity and compatibility with a range of substrates, this compound stands out as a valuable asset in both academic research and industrial processes.

Synonyms
(1R-(-)-trans-1,2-Diaminocyclohexane
CAS Number
20439-47-8
Purity
≥ 98% (GC)
Molecular Formula
C6H14N2
Molecular Weight
0
MDL Number
MFCD00062985
PubChem ID
4610
Melting Point
43 °C (Lit.)
Appearance
White or colorless to light yellow to light orange powder to lump to clear
Boiling Point
193 °C (Lit.)
Optical Rotation
[α]20D = -26 to -25 ° (C = 5 in 1mol/L HCl)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(1R-(-)-trans-1,2-Diaminocyclohexane
CAS Number
20439-47-8
Purity
≥ 98% (GC)
Molecular Formula
C6H14N2
Molecular Weight
0
MDL Number
MFCD00062985
PubChem ID
4610
Melting Point
43 °C (Lit.)
Appearance
White or colorless to light yellow to light orange powder to lump to clear
Boiling Point
193 °C (Lit.)
Optical Rotation
[α]20D = -26 to -25 ° (C = 5 in 1mol/L HCl)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(1R,2R)-(-)-1,2-Cyclohexanediamine is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of chiral drugs that require specific stereochemistry for efficacy.
  • Ligand Formation: It is used in coordination chemistry to form ligands for metal complexes, which are essential in catalysis and materials science, enhancing reaction selectivity and efficiency.
  • Polymer Chemistry: The compound acts as a building block in the production of polyamides and other polymers, contributing to materials with improved mechanical properties and thermal stability.
  • Analytical Chemistry: It is employed as a chiral resolving agent in chromatography, allowing researchers to separate and analyze enantiomers effectively, which is crucial in quality control processes.
  • Biochemical Applications: The compound is used in the synthesis of various biochemicals, aiding in the development of new diagnostic tools and therapeutic agents, particularly in the field of cancer research.

Citations