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Catalog Number:
40823
CAS Number:
112022-83-0
(R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine
Purity:
≥ 97% (Assay by titration)
Synonym(s):
(R)-3,3-Diphenyl-1-methyltetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, (R)-Me-CBS Catalyst
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$38.06 /1G
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Product Information

(R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine is a versatile compound with significant applications in organic synthesis and medicinal chemistry. This chiral oxazaborolidine derivative is particularly valued for its ability to facilitate asymmetric reactions, making it an essential tool for researchers aiming to produce enantiomerically pure compounds. Its unique structure allows for the stabilization of transition states in catalytic processes, enhancing reaction efficiency and selectivity.

In the pharmaceutical industry, this compound has shown promise in the development of novel drug candidates, particularly in the synthesis of complex molecules with high stereochemical fidelity. Its application extends to the production of biologically active compounds, where precise control over stereochemistry is crucial. Researchers and industry professionals can leverage (R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine to streamline their synthetic pathways, reduce waste, and improve overall yields in their projects.

Synonyms
(R)-3,3-Diphenyl-1-methyltetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, (R)-Me-CBS Catalyst
CAS Number
112022-83-0
Purity
≥ 97% (Assay by titration)
Molecular Formula
C18H20BNO
Molecular Weight
277.17
MDL Number
MFCD00078440
PubChem ID
551090
Melting Point
85 - 95 °C (Lit.)
Appearance
White to off-white crystal
Optical Rotation
[α]20D = 66 - 73 ° (C = 1 in MeOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(R)-3,3-Diphenyl-1-methyltetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, (R)-Me-CBS Catalyst
CAS Number
112022-83-0
Purity
≥ 97% (Assay by titration)
Molecular Formula
C18H20BNO
Molecular Weight
277.17
MDL Number
MFCD00078440
PubChem ID
551090
Melting Point
85 - 95 °C (Lit.)
Appearance
White to off-white crystal
Optical Rotation
[α]20D = 66 - 73 ° (C = 1 in MeOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine is widely utilized in research focused on:

  • Asymmetric Synthesis: This compound is valuable in asymmetric synthesis, allowing chemists to create chiral molecules efficiently. Its unique structure facilitates the development of pharmaceuticals with specific stereochemistry, enhancing drug efficacy and reducing side effects.
  • Catalysis: It serves as a catalyst in various chemical reactions, particularly in the formation of carbon-carbon bonds. This application is crucial in the production of fine chemicals and agrochemicals, providing a more sustainable approach compared to traditional methods.
  • Material Science: The compound can be used in the development of advanced materials, such as polymers and coatings. Its properties contribute to improved durability and performance, making it suitable for applications in electronics and automotive industries.
  • Medicinal Chemistry: In drug discovery, it plays a role in the design of new therapeutic agents. Its ability to modify molecular frameworks can lead to the identification of novel compounds with potential anti-cancer or anti-inflammatory activities.
  • Environmental Chemistry: The compound has potential applications in environmental remediation, particularly in the degradation of pollutants. Its reactivity can be harnessed to develop methods for cleaning up contaminated sites, contributing to sustainability efforts.

Citations