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Catalog Number:
40737
CAS Number:
37002-48-5
(2S,3S)-(+)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol
Purity:
≥ 95% (GC)
Synonym(s):
(4S,5S)-(+)-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane, (2S,3S)-(+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane, (+)-DIOP
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Product Information

The compound (2S,3S)-(+)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol is a versatile ligand widely utilized in asymmetric synthesis and catalysis. Its unique structure, featuring two diphenylphosphino groups, enhances its ability to form stable complexes with transition metals, making it an essential component in various catalytic reactions. This compound is particularly valuable in the pharmaceutical industry for the synthesis of chiral intermediates, which are crucial for the development of enantiomerically pure drugs. Additionally, its application extends to organic synthesis, where it facilitates the formation of carbon-carbon bonds, thereby improving reaction efficiency and selectivity.

Researchers and industry professionals benefit from the compound's high stability and reactivity, which allow for the optimization of reaction conditions and improved yields. Its ability to function in diverse environments makes it a preferred choice for those looking to enhance their synthetic methodologies. With its proven track record in catalysis, this compound stands out as a reliable tool for advancing research and development in various chemical applications.

Synonyms
(4S,5S)-(+)-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane, (2S,3S)-(+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane, (+)-DIOP
CAS Number
37002-48-5
Purity
≥ 95% (GC)
Molecular Formula
C31H32O2P2
Molecular Weight
498.54
MDL Number
MFCD00009760
PubChem ID
122582
Melting Point
88 - 92 °C
Appearance
White to off-white crystal
Conditions
Store at RT
General Information
Synonyms
(4S,5S)-(+)-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane, (2S,3S)-(+)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane, (+)-DIOP
CAS Number
37002-48-5
Purity
≥ 95% (GC)
Molecular Formula
C31H32O2P2
Molecular Weight
498.54
MDL Number
MFCD00009760
PubChem ID
122582
Melting Point
88 - 92 °C
Appearance
White to off-white crystal
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(2S,3S)-(+)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol is widely utilized in research focused on:

  • Catalysis: This compound serves as an effective ligand in various catalytic processes, enhancing reaction rates and selectivity in organic synthesis, particularly in asymmetric reactions.
  • Pharmaceutical Development: It plays a crucial role in the development of new drugs, especially in the synthesis of complex organic molecules that are essential for medicinal chemistry.
  • Material Science: The compound is used in the formulation of advanced materials, contributing to the development of polymers and composites with improved properties.
  • Environmental Chemistry: It is applied in the design of catalysts for environmental remediation processes, helping to break down pollutants more efficiently.
  • Research and Development: This chemical is a valuable tool in academic and industrial laboratories for exploring new chemical reactions and mechanisms, aiding in the advancement of chemical knowledge.

Citations