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Catalog Number:
40388
CAS Number:
227305-69-3
2,3-Dihydrobenzofuran-5-boronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
2,3-Dihydrobenzo[b]furan-5-boronic, 2,3-Dihydro-1-benzofuran-5-ylboronic acid
Documents
$161.64 /200MG
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Product Information

2,3-Dihydrobenzofuran-5-boronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the development of complex organic molecules, including pharmaceuticals and agrochemicals. Its unique structure, featuring a benzofuran moiety, enhances its reactivity and selectivity in various chemical transformations, providing researchers with a powerful tool for synthesizing diverse compounds.

In addition to its synthetic applications, 2,3-Dihydrobenzofuran-5-boronic acid has shown potential in the development of biologically active molecules, particularly in the field of drug discovery. Its boronic acid functionality allows for the formation of reversible covalent bonds with diols, which is advantageous in designing inhibitors and other therapeutic agents. This compound's ability to facilitate the creation of novel structures while maintaining high specificity makes it a valuable asset for researchers and industry professionals aiming to innovate in their respective fields.

Synonyms
2,3-Dihydrobenzo[b]furan-5-boronic, 2,3-Dihydro-1-benzofuran-5-ylboronic acid
CAS Number
227305-69-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C8H9BO3
Molecular Weight
163.97
MDL Number
MFCD02681979
PubChem ID
2773380
Melting Point
240 °C (Lit.)
Appearance
White to almost white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2,3-Dihydrobenzo[b]furan-5-boronic, 2,3-Dihydro-1-benzofuran-5-ylboronic acid
CAS Number
227305-69-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C8H9BO3
Molecular Weight
163.97
MDL Number
MFCD02681979
PubChem ID
2773380
Melting Point
240 °C (Lit.)
Appearance
White to almost white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2,3-Dihydrobenzofuran-5-boronic acid is widely utilized in research focused on:

  • Drug Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in developing treatments for neurological disorders.
  • Organic Synthesis: It is employed in Suzuki coupling reactions, which are essential for creating complex organic molecules, making it valuable in the production of agrochemicals and fine chemicals.
  • Bioconjugation: The boronic acid functionality allows for selective binding to diols, facilitating the development of targeted drug delivery systems in biomedical applications.
  • Material Science: It is used in the formulation of advanced materials, including sensors and polymers, due to its unique chemical properties that enhance material performance.
  • Analytical Chemistry: This compound is beneficial in the development of analytical methods for detecting specific biomolecules, aiding in diagnostics and research in biochemistry.

Citations