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Catalog Number:
40362
CAS Number:
1003043-40-0
2-Chloro-3-methylpyridine-5-boronic acid
Purity:
98 - 105% (Assay by titration)
Synonym(s):
(6-Chloro-5-methylpyridin-3-yl)boronic acid
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Product Information

2-Chloro-3-methylpyridine-5-boronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the formation of complex organic molecules. Its unique structure, featuring a chloro and methyl group on the pyridine ring, enhances its reactivity and selectivity in various chemical transformations. Researchers and industry professionals utilize this compound in the development of pharmaceuticals, agrochemicals, and advanced materials, where precision and efficiency are paramount.

The compound's boronic acid functionality allows for the formation of stable complexes with diols, which is particularly beneficial in the synthesis of biologically active compounds. Additionally, its application in the development of targeted therapies highlights its importance in the pharmaceutical industry. With its favorable properties and broad applicability, 2-Chloro-3-methylpyridine-5-boronic acid stands out as a valuable tool for chemists seeking to innovate and streamline their research and development processes.

Synonyms
(6-Chloro-5-methylpyridin-3-yl)boronic acid
CAS Number
1003043-40-0
Purity
98 - 105% (Assay by titration)
Molecular Formula
C6H7BClNO2
Molecular Weight
171.39
MDL Number
MFCD03411564
PubChem ID
17750236
Melting Point
180 - 183 °C
Appearance
White to almost white crystalline powder
Conditions
Store at RT
General Information
Synonyms
(6-Chloro-5-methylpyridin-3-yl)boronic acid
CAS Number
1003043-40-0
Purity
98 - 105% (Assay by titration)
Molecular Formula
C6H7BClNO2
Molecular Weight
171.39
MDL Number
MFCD03411564
PubChem ID
17750236
Melting Point
180 - 183 °C
Appearance
White to almost white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Chloro-3-methylpyridine-5-boronic acid is widely utilized in research focused on:

  • Synthetic Chemistry: It serves as a key building block in the synthesis of various organic compounds, particularly in the development of pharmaceuticals and agrochemicals.
  • Catalysis: This compound is used in palladium-catalyzed cross-coupling reactions, which are essential for forming carbon-carbon bonds in complex organic molecules.
  • Medicinal Chemistry: Researchers leverage its unique properties to design and optimize drug candidates, particularly in targeting specific biological pathways.
  • Material Science: It is employed in the development of advanced materials, including polymers and nanomaterials, due to its ability to modify surface properties.
  • Environmental Applications: The compound is explored for its potential in developing sensors for detecting pollutants, contributing to environmental monitoring efforts.

Citations