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Catalog Number:
40222
CAS Number:
385370-80-9
2-Chloro-6-methoxyphenylboronic acid
Purity:
95 - 105% (Assay by titration)
Synonym(s):
2-Chloro-6-methoxybenzeneboronic acid
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Product Information

2-Chloro-6-methoxyphenylboronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals. Its unique structure, featuring a chloro and methoxy group, enhances its reactivity and selectivity, allowing researchers to create targeted compounds with precision.

In addition to its applications in synthetic chemistry, 2-Chloro-6-methoxyphenylboronic acid has shown promise in the development of novel therapeutic agents. Its ability to form stable complexes with various substrates makes it valuable in drug discovery and development processes. Researchers can leverage this compound to explore new pathways in medicinal chemistry, potentially leading to innovative treatments for various diseases. With its robust performance in cross-coupling reactions and its relevance in pharmaceutical research, this boronic acid derivative is an indispensable tool for chemists and industry professionals alike.

Synonyms
2-Chloro-6-methoxybenzeneboronic acid
CAS Number
385370-80-9
Purity
95 - 105% (Assay by titration)
Molecular Formula
C7H8BClO3
Molecular Weight
186.4
MDL Number
MFCD04039878
PubChem ID
3378271
Melting Point
165 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
2-Chloro-6-methoxybenzeneboronic acid
CAS Number
385370-80-9
Purity
95 - 105% (Assay by titration)
Molecular Formula
C7H8BClO3
Molecular Weight
186.4
MDL Number
MFCD04039878
PubChem ID
3378271
Melting Point
165 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Chloro-6-methoxyphenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound is instrumental in synthesizing various pharmaceutical agents, particularly in the development of anti-cancer drugs, where it helps in creating targeted therapies.
  • Organic Synthesis: It serves as a key building block in organic chemistry, facilitating the formation of complex molecules through Suzuki coupling reactions, which are essential in creating diverse organic compounds.
  • Material Science: The compound is used in the production of advanced materials, including polymers and nanomaterials, enhancing properties like strength and conductivity, which are crucial for electronics and coatings.
  • Bioconjugation: It plays a significant role in bioconjugation techniques, allowing researchers to attach biomolecules to surfaces or other molecules, which is vital in drug delivery systems and diagnostic applications.
  • Environmental Chemistry: This chemical is employed in the development of sensors for detecting pollutants, contributing to environmental monitoring and ensuring compliance with safety regulations.

Citations