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Catalog Number:
40206
CAS Number:
166744-78-1
4-Benzyloxy-2-fluorophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
4-Benzyloxy-2-fluorobenzeneboronic acid
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$29.34 /200MG
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Product Information

4-Benzyloxy-2-fluorophenylboronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals. Its unique structure, featuring a fluorine atom and a benzyloxy group, enhances its reactivity and selectivity in various chemical transformations, allowing researchers to create targeted compounds with precision.

In addition to its synthetic applications, 4-Benzyloxy-2-fluorophenylboronic acid has shown potential in the development of novel therapeutic agents, particularly in the field of cancer research. Its ability to form stable complexes with various substrates makes it a valuable tool for researchers aiming to explore new pathways in drug discovery. With its favorable properties and broad applicability, this compound is an excellent choice for professionals seeking to advance their research and development efforts in organic chemistry and related fields.

Synonyms
4-Benzyloxy-2-fluorobenzeneboronic acid
CAS Number
166744-78-1
Purity
97 - 105% (Assay by titration)
Molecular Formula
C13H12BFO3
Molecular Weight
246.04
MDL Number
MFCD02093064
PubChem ID
2737786
Melting Point
155 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
4-Benzyloxy-2-fluorobenzeneboronic acid
CAS Number
166744-78-1
Purity
97 - 105% (Assay by titration)
Molecular Formula
C13H12BFO3
Molecular Weight
246.04
MDL Number
MFCD02093064
PubChem ID
2737786
Melting Point
155 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Benzyloxy-2-fluorophenylboronic acid is widely utilized in research focused on:

  • Drug Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of targeted cancer therapies.
  • Organic Synthesis: It is employed in cross-coupling reactions, allowing chemists to create complex organic molecules efficiently, which is essential in materials science and medicinal chemistry.
  • Bioconjugation: The compound can be used to attach biomolecules to surfaces or other molecules, enhancing drug delivery systems and improving the efficacy of therapeutic agents.
  • Fluorescent Probes: Its unique properties make it suitable for creating fluorescent probes, which are valuable in biological imaging and diagnostics, helping researchers visualize cellular processes.
  • Environmental Monitoring: This chemical can be utilized in the detection of environmental pollutants, aiding in the development of sensors that monitor water quality and other ecological factors.

Citations