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Catalog Number:
40142
CAS Number:
146140-95-6
2-(Pivalamido)phenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
2-(Pivaloylamino)phenylboronic acid, 2-(2,2,2-Trimethylacetamido)phenylboronic acid
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Product Information

2-(Pivalamido)phenylboronic acid is a versatile compound recognized for its unique properties and applications in various fields, particularly in medicinal chemistry and organic synthesis. This boronic acid derivative features a pivalamido group, which enhances its reactivity and solubility, making it an ideal candidate for coupling reactions and as a building block in the synthesis of complex organic molecules. Its ability to form stable complexes with diols is particularly valuable in the development of sensors and in the field of drug discovery, where it can facilitate the identification of biologically active compounds.

Researchers and industry professionals can leverage 2-(Pivalamido)phenylboronic acid in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. Its unique structural attributes allow for selective reactions, providing an edge over traditional boronic acids in specific applications. The compound's stability and reactivity make it suitable for use in high-throughput screening processes, contributing to more efficient research and development cycles. With its growing relevance in the synthesis of novel compounds, 2-(Pivalamido)phenylboronic acid stands out as a valuable tool for innovation in chemical research.

Synonyms
2-(Pivaloylamino)phenylboronic acid, 2-(2,2,2-Trimethylacetamido)phenylboronic acid
CAS Number
146140-95-6
Purity
97 - 105% (Assay by titration)
Molecular Formula
C11H16BNO3
Molecular Weight
221.06
MDL Number
MFCD01114645
PubChem ID
4193502
Melting Point
271 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-(Pivaloylamino)phenylboronic acid, 2-(2,2,2-Trimethylacetamido)phenylboronic acid
CAS Number
146140-95-6
Purity
97 - 105% (Assay by titration)
Molecular Formula
C11H16BNO3
Molecular Weight
221.06
MDL Number
MFCD01114645
PubChem ID
4193502
Melting Point
271 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-(Pivalamido)phenylboronic acid is widely utilized in research focused on:

  • Drug Development: This compound plays a crucial role in the synthesis of boronic acid derivatives, which are important in the development of pharmaceuticals, particularly for targeting cancer cells.
  • Chemical Synthesis: It serves as a versatile building block in organic synthesis, enabling the formation of complex molecules through cross-coupling reactions, which are essential in various chemical industries.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, enhancing the functionality of drugs and diagnostics.
  • Sensor Technology: It is applied in the development of sensors for detecting glucose and other biomolecules, providing a reliable method for monitoring health conditions such as diabetes.
  • Material Science: This chemical contributes to the creation of advanced materials with specific properties, such as improved thermal stability and mechanical strength, beneficial in electronics and construction.

Citations